Protein Alignment CG5348 and slc24a6a

DIOPT Version :9

• Sequence 1: NP_611156.3
• Gene: CG5348 / 36877
• FlyBaseID: FBgn0034156
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_009289475.1
• Gene: slc24a6a / 561209
• ZFINID: ZDB-GENE-100922-39
• Length: 639
• Species: Danio rerio
• Alignment Length: 623
• Identity: 123/623 - (19%)
• Similarity: 226/623 - (36%)
• Gaps: 177/623 - (28%)

  Fly    74 INQFQEMIF---------IALFVAFCFQILVLLIYTI----NVYYSPALKAVSRFLHMNEHLAGV 125
            |::|.:.||         |.|.| ||   .|.:.|.:    :|::.|:|:.:...||::|.:||.
Zfish    89 IHEFPQDIFTKGQRRHGAILLHV-FC---AVYMFYALAIVCDVFFVPSLEKICENLHLSEDVAGA 149

  Fly   126 TLMAFGNTSADFFANLASVERHVPVFANN--------LSSALFVITISGGL--IFYISPFKMNSY 180
            |.||.|:::.:.|.:|      :.||...        :.||:|.|.:..|:  ||......:..:
Zfish   150 TFMAAGSSAPELFTSL------IGVFITKGDLGVGTIVGSAVFNILVIIGVCGIFAGQTITLTWW 208

  Fly   181 ETVRDILFLLLATLLMDYFAYTTNHFALGYEFKFFIVLLVY-------ISYIIINVADVYLL--- 235
            ...||.:|.:|:.|.                    ::|::|       .:.|:|::..||:|
Zfish   209 PLFRDSIFYILSVLA--------------------LILIIYDEKVIWWETIILISMYGVYILIMK 253

  Fly   236 -----------------QKTIASTRTKMQKLLDEKQTPEIALKLQDLERKLEYYSQDTRVEILEK 283
                             |..:.|:..:...:  .:.:|.....:..|::......||:.|.::::
Zfish   254 FNSQIWGWVEQRFGIPGQPCLVSSLRRDVSV--GEASPHCDTSMILLKKGQNAGGQDSPVVMVDE 316

  Fly   284 SSSISITRIRYT--TMRMIRNPRVSVNRR--------YTRNMKLDYTQS---------------- 322
            ..|:...:..::  ::|::..|..|...|        .|...:|...:|
Zfish   317 LMSLHPHQFSFSEASLRVMITPHFSPRTRLSMAGRMLITERQRLIRNRSPGDSSGSGAGDTPGQD 381

  Fly   323 -----------KNQGIFRDFFLALRPIKCQAWKQAELLNRVLLLIRAPAVVICTLYIPLVDYEME 376
                       :|.|........|...:.::  |...|.||       |.:..|.  |..|.|.|
Zfish   382 GPGMEAVPWGLENGGALESETQPLEEPRRRS--QGGELERV-------ADIEDTQ--PKDDEEDE 435

  Fly   377 KHGWNKLLNAINVVVNPALSISIFLSFMHRKGNFLWYISLQNTLIYGASSFVLTVPFAVFILFHA 441
            :....:......|...         .:...|..|.|.:|   .|:|      .|||..|
Zfish   436 EEADEEPFRPFTVPEG---------RWEQAKWMFSWPLS---CLLY------YTVPNCV------ 476

  Fly   442 RTDVPPSYHWVFTIMNLTGSMFLIFLCATEIDTVLEVIGNILSIDDNYMGATVKAFTGNLGTLFA 506
               :|....|.  ::....|...|.:.:..:..::.:|...|.|.|..||.|..|...::....|
Zfish   477 ---LPRWERWF--MVTFVASTLWIAVFSYLMVWMVTIISFTLDIPDVVMGITFLAAGTSVPDCMA 536

  Fly   507 NTAVAIHGYPKMAFASAIGGSFFTIVVTGNTVAYVRSLVGNRSEHHMEEYGEIAFIFLNMALFTI 571
            :..||..|...||.:::||.:.|.|::.......:|:||        .:||....|.....::::
Zfish   537 SLIVARQGMGDMAVSNSIGSNIFDILLGLGFPWALRTLV--------VDYGSTVSINSKGLVYSV 593

  Fly   572 LL-----WSTTLGFFAR-----RSMGLYSIGLYVVYLL 599
            :|     :.|.|.....     |.:||..:.||.::||
Zfish   594 ILLLASVFLTVLSVHLNHWRLDRRLGLGLMFLYAIFLL 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	29/113 (26%)
		Na_Ca_ex	458..603	CDD:279963	36/152 (24%)
slc24a6a	XP_009289475.1	Na_Ca_ex	<85..637	CDD:332332	123/623 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810