Protein Alignment CG5348 and slc24a1

DIOPT Version :9

• Sequence 1: NP_611156.3
• Gene: CG5348 / 36877
• FlyBaseID: FBgn0034156
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_009291877.2
• Gene: slc24a1 / 558299
• ZFINID: ZDB-GENE-060503-191
• Length: 741
• Species: Danio rerio
• Alignment Length: 687
• Identity: 120/687 - (17%)
• Similarity: 233/687 - (33%)
• Gaps: 239/687 - (34%)

  Fly    62 PYMRLLACDLKCINQFQEMIF---------IALFVAFCFQILVLLIYTINVYYSPALKAVSRFLH 117
            |:|:         .::.|.||         ::|.:.....:.|.|....:.::.|.|..::..|.
Zfish   149 PHMK---------GEYPEDIFSIEDRRKGWVSLHIFGMVYMFVSLAIVCDEFFVPTLGVITDKLA 204

  Fly   118 MNEHLAGVTLMAFGNTSADFFANLASVERHVPVFANN--------LSSALFVITISGGL--IFYI 172
            :::.:||.|.||.|.::.:.|.:|      :.||.::        :.||:|.|....|:  :|..
Zfish   205 ISDDVAGATFMAAGGSAPELFTSL------IGVFISHSNVGIGTIVGSAVFNILFVIGMCALFSR 263

  Fly   173 SPFKMNSYETVRDILFLLLATLLMDYFAYTTNHFALGYEFKFFI-VLLVYISYIIINVADVYLLQ 236
            ....:..:...||:.|.:|..:::  ..:..::..:.:|....: ...:|::::..||.    |:
Zfish   264 EMLHLTWWPLFRDVSFYILDLIML--IIFFLDNTIMWWESMMLVGGYALYVTFMKFNVQ----LE 322

  Fly   237 KTIASTRTKMQKLL----------------DEKQTPE----IALKLQ-DLER---KLEYYSQDTR 277
            :...|..:|.:.::                :|.:.||    ..|||: .|:|   ....::...|
Zfish   323 RAFKSQLSKHKSIVKVIAVEEPEKDNGTSGEENRPPEPEDKNRLKLKPTLQRGGSSASLHNSTMR 387

  Fly   278 VEILE-------------------KSSSISITRIRYTTMRMIRNPRVSVNRRYTRNMKLDYT--- 320
            ..|.:                   |:.|....::::.....|.|   .:.|....|.|.:.:
Zfish   388 NTIFQLMIHTLDPLGEESVFNGDAKARSSLECKVKFKDKAQILN---DMARGKVENKKKEKSGEG 449

  Fly   321 -----QSK--------------NQGIFRDFFLALRPIKCQAWKQAELLNRVLLLIRAPAVVICTL 366
                 |:|              ||             |.:|.|
Zfish   450 DDQSEQTKDSKDAPPGAKDEDTNQ-------------KSEAQK---------------------- 479

  Fly   367 YIPLVDYEMEKHGWNKLLNAINVVVNPALS----------------------------------- 396
                 |.::...|.::         ||..|
Zfish   480 -----DGDIAAGGGSE---------NPGGSDNSGDDDEDDSDEESDDDDDDDDDDDDDDDENEDE 530

  Fly   397 --------ISIFLSFMHRKGNFLWYISLQNTLIYGASSFVLTVPFAVFILFHARTDVPPSYHWVF 453
                    :|:......||         |.|.:     |:|.:   ||.|:....||.......|
Zfish   531 AGEDGDEPLSLEWPDTRRK---------QATYL-----FLLPI---VFPLWLTVPDVRNPASKKF 578

  Fly   454 TIMNLTGSMFLIFLCATEIDTVLEVIGNILSIDDNYMGATVKAFTGNLGTLFANTAVAIHGYPKM 518
            .::...||:..|.:.:..:......:|..:.|.:..||.|:.|...::..|..:..||..|...|
Zfish   579 FVITFLGSIVWIAIFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDM 643

  Fly   519 AFASAIGGSFFTIVVTGNTVAYVR-SLVGNRSEHHMEEYG---EIAFIFLNMALFTIL-----LW 574
            |.:|::|.:.|.|.: |..|.::. |...:.:...:...|   .|..:|| |.||.|:     .|
Zfish   644 AVSSSVGSNIFDITM-GLPVPWLMFSFFHSFAPVPVSSNGLFCAIVLLFL-MLLFVIISIAACKW 706

  Fly   575 --STTLGFFARRSMGLYSIGLYVVYLLFVTLVHEEVI 609
              :..|||    :|.:    ||.|:|:...::.:.:|
Zfish   707 RMNKVLGF----TMFI----LYFVFLVLSVMLEDRII 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	22/109 (20%)
		Na_Ca_ex	458..603	CDD:279963	39/155 (25%)
slc24a1	XP_009291877.2	Na_Ca_ex	<112..741	CDD:332332	120/687 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910