Protein Alignment CG5348 and slc24a3

DIOPT Version :9

• Sequence 1: NP_611156.3
• Gene: CG5348 / 36877
• FlyBaseID: FBgn0034156
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_685302.4
• Gene: slc24a3 / 557196
• ZFINID: ZDB-GENE-090312-67
• Length: 660
• Species: Danio rerio
• Alignment Length: 645
• Identity: 109/645 - (16%)
• Similarity: 209/645 - (32%)
• Gaps: 209/645 - (32%)

  Fly    70 DLKC----INQFQEMIF---------IALFVAFCFQILVLLIYTINVYYSPALKAVSRFLHMNEH 121
            |..|    |::|.:.||         :||.|.....:...|....:.|:.|:|:.:...||::|.
Zfish    99 DKNCTPPGIHEFPDDIFTQQERLEGAVALHVLCAMYMFYALALVCDDYFVPSLEKICERLHLSED 163

  Fly   122 LAGVTLMAFGNTSADFFANLASVERHVPVFANN--------LSSALF----VITISGGLIFYISP 174
            :||.|.||.|:::.:.|.::      :.||...        :.||:|    :|.:.|  ||....
Zfish   164 VAGATFMAAGSSAPELFTSV------IGVFITKGDVGVGTIVGSAVFNILCIIGVCG--IFTAQA 220

  Fly   175 FKMNSYETVRDILFLLLATLLMDYFAYTTNHFALGYEFKFFIVL-LVYISYIIINVADVYLLQK- 237
            .:::.:..:||..:..:|...:..|.|  :.....:|....||| ||||..:..|...|:.:::
Zfish   221 VRLSCWTLMRDSTYYTIAVATLIVFIY--DEKVTWWESLILIVLYLVYILIMKFNSRVVHFIERR 283

  Fly   238 -----TIASTRTKMQKLLDEKQTPEIALKLQDLERK---------LEYYS-----QDTRVEILEK 283
                 .:.:.......:.|......:.||..:..||         |..|.     .:..:.|:..
Zfish   284 KKNPANLGNGTASNTDIDDGCDATVVLLKKANFHRKPSVLMVDELLSAYPHQLTFSEAGMRIMIT 348

  Fly   284 SSSISITRIRYTTMRMIRNPRVSVNRRYT------------------------------------ 312
            |.....||:...:..:|...:..:|.|::
Zfish   349 SHFSPRTRLTMASRMLITERQRLINSRFSNGDSEVTVKMPGKRGVENGLAGPDRGLNGRKGGHHD 413

  Fly   313 ----------------------RNMKLDYTQSKNQGIFRDFFLALRPIKCQAWKQAELLNRVLLL 355
                                  .|.:.:..:.:|:|
Zfish   414 DDRGGAEAGTDTENENEDNENNENDEEEEEEDENEG----------------------------- 449

  Fly   356 IRAPAVVICTLYIPLVDYEMEKHGWNKLLNAINVVVNPALSISIFLSFMHRKGNFLWYISLQNTL 420
                         |.|.:.....|.|||
Zfish   450 -------------PYVPFRCPGGGINKL------------------------------------- 464

  Fly   421 IYGASSFVLTVPFAVFILFHARTDVPPSYHWVFTIMNLTGSMFLIFLCATEIDTVLEVIGNILSI 485
                 .::|..|.::.:.|.......|.:...:.:..::.::::.|.....: .::.|||..:.|
Zfish   465 -----KWLLAWPLSMLLFFTVPNSANPRWERWYMVSFISSTIWIAFFSYIMV-WMVTVIGYTMGI 523

  Fly   486 DDNYMGATVKAFTGNLGTLFANTAVAIHGYPKMAFASAIGGSFFTIVV-TGNTVAYVRSLVGNRS 549
            .|..||.|..|...::....|:..||..|...||.:::||.:.|.|:: .|...|.....:...|
Zfish   524 PDVIMGITFLAAGTSVPDCLASLIVARQGMGDMAISNSIGSNVFDILIGLGLPWALQTLAINYGS 588

  Fly   550 EHHMEEYGEIAFIFLNMALFTILLWSTTLGFFAR-----RSMGLYSIGLYVVYLLFVTLV 604
            ..|:...|    :..::.|....::.|.||....     :.:|...:.:|.|:|.|..|:
Zfish   589 TIHLNSKG----LIFSVGLLLASVFLTVLGVHLNNWKLDKRLGFACLLMYAVFLCFSILI 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	25/111 (23%)
		Na_Ca_ex	458..603	CDD:279963	34/150 (23%)
slc24a3	XP_685302.4	TIGR00367	127..637	CDD:273039	98/608 (16%)
		Na_Ca_ex	128..270	CDD:279963	37/151 (25%)
		Na_Ca_ex	491..643	CDD:279963	34/156 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810