Protein Alignment CG5348 and Slc24a5

DIOPT Version :9

• Sequence 1: NP_611156.3
• Gene: CG5348 / 36877
• FlyBaseID: FBgn0034156
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_778199.2
• Gene: Slc24a5 / 317750
• MGIID: 2677271
• Length: 501
• Species: Mus musculus
• Alignment Length: 578
• Identity: 102/578 - (17%)
• Similarity: 203/578 - (35%)
• Gaps: 184/578 - (31%)

  Fly    69 CDLKCINQFQEMIF---------IALFVAFCFQILVLLIYTINV----YYSPALKAVSRFLHMNE 120
            |.:...::|.|..|         |.::    |.|::.:...|::    |:.|:|:.:|..|.:::
Mouse    46 CAVSPASEFPEGFFTKQESTDGGIVIY----FLIILYMCMAISIVCDKYFLPSLEIISDSLGLSQ 106

  Fly   121 HLAGVTLMAFGNTSADFFANLASVERHVPVFANNLSSALFVITISGGLIFYISPFKMNSYETVRD 185
            .:||.|.||.|:::.:.      |...:.||..  ...:.:.||.|..|:              :
Mouse   107 DVAGATFMAAGSSAPEL------VTAFLGVFIT--KGDIGISTILGSAIY--------------N 149

  Fly   186 ILFLLLATLLMDYFAYTTNHFALGYEFKFFIV----------------------LLVYISYIIIN 228
            :|.:..|..|:.....|.:.:.|..:...:.|                      ||:|..|:::.
Mouse   150 LLGICAACGLLSNMVSTLSCWPLFRDCAVYAVSVGAVFGIIFDNRIYWYEGAGLLLIYGLYVLLL 214

  Fly   229 VADVYL---LQKTIASTRTKMQKLLDEKQTPEIALKLQDLERKLEYYSQDTRVE--ILEKSSSIS 288
            ..|..:   :.||.:.....:.:.::|:...:..|..:| |.:| :..:.:|.:  |.::.|..|
Mouse   215 CFDTTISRHVMKTCSPCCPCLARAMEERIEQQTLLGWED-ESQL-FIRRQSRTDSGIFQEDSGYS 277

  Fly   289 ITRIRYTTMRMIRNPRVSVNRRYTRNMKLDYTQSKNQGIFRDFFLALRPIKCQAWKQAELLNRVL 353
                           ::|::......:..|                  |....:..:|: |.|:.
Mouse   278 ---------------QLSLSLHGLSQVSED------------------PPSVFSMPEAD-LRRIF 308

  Fly   354 LLIRAPAVVICTLYIPLVDYEMEKHGWNKLLNAINVVVNPALSISIFLSFMHRKGNFLWYISLQN 418
            .::..|.:.:..|..|    :..:..|.      |..|     |:.|:|       .||
Mouse   309 WVLSLPIITLLALTTP----DCRRKFWK------NYFV-----ITFFMS-------ALW------ 345

  Fly   419 TLIYGASSFVLTVPFAVFILFHARTDVPPSYHWVFTIMNLTGSMFLIFLCATEIDTVLEVIGNIL 483
               ..|.:::|.                    |:.|                       |.|..|
Mouse   346 ---ISAFTYILV--------------------WMVT-----------------------VTGETL 364

  Fly   484 SIDDNYMGATVKAFTGNLGTLFANTAVAIHGYPKMAFASAIGGSFFTIVVTGNTVAYVRSLVGNR 548
            .|.|..||.|:.|...::.....:..||..|...||.::.:|.:.|.::..| ...::::...|.
Mouse   365 GIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFDMLCLG-LPWFIKTAFTNA 428

  Fly   549 S---EHHMEEYGEIAFIFLNMALFTILLWSTTLGFFARRSMGLYSIGLYVVYLLFVTL 603
            |   |.:.:....|. |.||:::..:.|.....|:...|.:|:..:   |:||...||
Mouse   429 SAPIEVNSKGLTYIT-ISLNISILFLFLAVHFNGWKLDRKLGVVCL---VLYLGLATL 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	21/103 (20%)
		Na_Ca_ex	458..603	CDD:279963	31/147 (21%)
Slc24a5	NP_778199.2	Na_Ca_ex	72..216	CDD:279963	31/169 (18%)
		TIGR00367	77..477	CDD:273039	91/536 (17%)
		Na_Ca_ex	334..485	CDD:279963	43/218 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810