DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5348 and Slc24a1

DIOPT Version :9

Sequence 1:	NP_611156.3	Gene:	CG5348 / 36877	FlyBaseID:	FBgn0034156	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_659062.1	Gene:	Slc24a1 / 214111	MGIID:	2384871	Length:	1130	Species:	Mus musculus

Alignment Length:	242	Identity:	53/242 - (21%)
Similarity:	107/242 - (44%)	Gaps:	43/242 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 FIALFVAFCFQILVLLIYTINVYYSPALKAVSRFLHMNEHLAGVTLMAFGNTSADFFANLASVER 146
            ::.|.:.....:.|.|....:.|:.|||..::..|.::|.:||.|.||.|.::.:.|.:|
Mouse   421 WVVLHIFGMMYVFVALAIVCDEYFVPALGVITHKLQISEDVAGATFMAAGGSAPELFTSL----- 480

  Fly   147 HVPVFANN--------LSSALFVITISGGLIFYISPFKMNSYETV--------RDILFLLL-ATL 194
             :.||.::        :.||:|      .::|.|....:.|.|.:        ||:.|.:| .::
Mouse   481 -IGVFISHSNVGIGTIVGSAVF------NILFVIGTCALFSREILNLTWWPLFRDVSFYILDLSM 538

  Fly   195 LMDYFAYTTNHFALGYEFKFFIVLLVYISYIII----NVADVYLLQKTIASTRTKMQKLLDEKQT 255
            |:.:|   .:.|...:|  ..::||.|..|:..    ...::::.::.......|:..|.|..:.
Mouse   539 LIVFF---LDSFIAWWE--SLLLLLAYALYVFTMKWNKQIELWVKEQLSRRPVAKVMALGDLSKP 598

  Fly   256 PEIALKLQDLE--RKLEYYSQDTRVEILEKSSSISITRIRYTTMRMI 300
            .|.|::..:.:  :||:..|..||.   ..|:|:..:.||.|...::
Mouse   599 SEDAVEENEQQDSKKLKLPSVLTRG---SSSASLHNSIIRNTIYHLM 642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	26/115 (23%)
CG5348	NP_611156.3	Na_Ca_ex	458..603	CDD:279963
Slc24a1	NP_659062.1	2A1904	1..1130	CDD:273344	53/242 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810