Protein Alignment CG5348 and ncx-10

DIOPT Version :9

• Sequence 1: NP_611156.3
• Gene: CG5348 / 36877
• FlyBaseID: FBgn0034156
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001256094.1
• Gene: ncx-10 / 190821
• WormBaseID: WBGene00003575
• Length: 668
• Species: Caenorhabditis elegans
• Alignment Length: 665
• Identity: 131/665 - (19%)
• Similarity: 265/665 - (39%)
• Gaps: 156/665 - (23%)

  Fly    33 CFAANNFPFEERCEFVQKAEDCNSSTNVIPYMRLLACDLKCINQFQEMIFIALFVAFCFQILVLL 97
            |....::..|:.|.:::..:|.......:.:...:.|:   .::...:|.|.:.:.:...:.|::
 Worm    57 CLIQKHWTREDTCAYIKCNKDACEGGGYLQWSEYIKCE---HSRSIRIILIIISIIYLLFLFVVM 118

  Fly    98 IYTINVYYSPALKAVSRFLHMNEHLAGVTLMAFGNTSADFFANLASV-----ERHVPVFANNLSS 157
            ....:.::||::..:.|.|.::|.:||||.:||||.:.|.|.::|||     .:......:.:..
 Worm   119 TVVADDFFSPSIAGIVRHLKISESIAGVTFLAFGNGAPDVFGSIASVITTPKPKADLAIGDIIGG 183

  Fly   158 ALFVITISGGLIFYISPFKMNSYETVRDILFLLLATLLMDYFAYTTNHFALGYEFKFFIVLLVYI 222
            .:||.|:....|.....|::....|:|||:|.::|.:.:..:..|.||..:.....|   |.:|.
 Worm   184 GIFVTTVVLSAIILTKSFRIAILATIRDIVFFIIADIFLAIWFLTFNHVEIWMPLTF---LGLYA 245

  Fly   223 SYIIINVADVYLLQKTIASTRTKMQKLLDEKQTPEIALKLQDLERKLEYYSQDTRVEILEKSSSI 287
            :|::                             ..|.::|....||   .::..::|...|.|::
 Worm   246 AYVV-----------------------------SVILMRLNSKRRK---RARHEKIENARKESAM 278

  Fly   288 SITRIRYTT-----------MRMIRNPRVSVNRRYTRNMK--------------LDYTQSKNQGI 327
            :....:.:|           :....|.::|   ..|.|:|              :|.| |.::|:
 Worm   279 NHHTHKISTFIGFFMDYAHVINFFANNKIS---SMTNNVKNFLDGKEDSLEDGLVDET-SDDEGV 339

  Fly   328 FRDF-----------------FLALRPIKCQAWKQAELLNRVLLLIR------------------ 357
            ..:|                 |..:..|:.:.||..|.:..|...:|
 Worm   340 EAEFHYAHRHVYKSYDEASLAFTDVEEIQPKTWKSWEWVRDVRNHLRPWPGNDEFYEMNYFSRFI 404

  Fly   358 APAVVICTLYIPLV--DYEMEKHGWNKLLNAINVVVNPALSISIFLSFMHRKGNF-----LWYIS 415
            ....||.|.::.|.  ..||.   |:|.:..|:...  ::.:::|...:..|..|     ||
 Worm   405 TVVAVIPTFFLKLTIPSNEMP---WSKPILIIHCFC--SIQLALFAVQISAKSPFHGSPGLW--- 461

  Fly   416 LQNTLIYGASSFVLTVPFAVFILFHARTDVPPSYH-WVFTIMNLTGSMFLIFLCATEIDTVLEVI 479
                 :||   .::::..::..|.....|....|: .|::.:....|:..|:..::||..|:.:|
 Worm   462 -----LYG---LLISIILSLLALRFTPLDREQKYYREVYSYLGFLMSIAWIYTISSEIINVITMI 518

  Fly   480 GNILSIDDNYMGATVKAFTGNLGTLFANTAVAIHGYPKMAFASAIGGSFFT--------IVVTGN 536
            |....:....:|.|:.|::..:|.:.::.||...|:||||.|:||||..|:        |.:|
 Worm   519 GVATGVSQEILGLTIMAWSNCIGDIVSDVAVVKQGFPKMAMAAAIGGPLFSKLYSRPCQIKIT-- 581

  Fly   537 TVAYVRSLV-------------GNRSEHHMEEYGEIAFIFLNMALFTILLWSTTLGFFARRSMGL 588
              .|:..|:             |.:.:..:.....:..:||.::|||.|:......|..|....:
 Worm   582 --TYISDLLIGFGLPFTIACLQGKQIDLIITPVYRLLMLFLAISLFTSLIAIFVQRFKVRWPHAV 644

  Fly   589 YSIGLYVVYLLFVTL 603
            ..:.::|.:|:||.|
 Worm   645 ALLTVFVAFLIFVLL 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	26/104 (25%)
		Na_Ca_ex	458..603	CDD:279963	41/165 (25%)
ncx-10	NP_001256094.1	PLN03151	35..571	CDD:215604	113/571 (20%)
		Na_Ca_ex	113..253	CDD:279963	37/171 (22%)
		Na_Ca_ex	492..659	CDD:279963	41/170 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I5893
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41602
Inparanoid	1	1.050	162	1.000	Inparanoid score	I2840
Isobase	1	0.950	-	0	Normalized mean entropy	S4675
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm4752
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.930