Protein Alignment CG5348 and slc24a4b

DIOPT Version :9

• Sequence 1: NP_611156.3
• Gene: CG5348 / 36877
• FlyBaseID: FBgn0034156
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_002665845.2
• Gene: slc24a4b / 100334346
• ZFINID: ZDB-GENE-081031-75
• Length: 636
• Species: Danio rerio
• Alignment Length: 615
• Identity: 122/615 - (19%)
• Similarity: 218/615 - (35%)
• Gaps: 195/615 - (31%)

  Fly    69 CDLKCINQFQEMIF---------IALFVAFCFQILVLLIYTINVYYSPALKAVSRFLHMNEHLAG 124
            |....|::|.:.:|         :.|.:.....:.:.|....:.|:..:|:.:...|:::|.:||
Zfish   130 CTEPAIHEFPDDVFTNAERKSGAVLLHIIAALYMFLALAIVCDDYFVTSLEKICEKLNLSEDVAG 194

  Fly   125 VTLMAFGNTSADFFANLASVERHVPVFANN--------LSSALF----VITISGGLIFYISPFKM 177
            .|.||.|:::.:.||::      :.||..:        :.||:|    :|.:.|  ||......:
Zfish   195 ATFMAAGSSAPELFASV------IGVFITHGDVGVGTIVGSAVFNILCIIGVCG--IFAGQVVLL 251

  Fly   178 NSYETVRDILFLLLATLLMDYFAYTTNHFALGYEFKFFIVLLVYISYIIINVADVYLLQKTIAST 242
            ..:...||..|.:|:.:.:..|.|  :...:.:|  ..:::::|..||:            |...
Zfish   252 TWWAVFRDSFFYILSVVALIVFIY--DEKIVWWE--SLVLVVMYACYIL------------IMKF 300

  Fly   243 RTKMQKLLDEKQTPEIA-------LKLQDLERKLEYYSQDTRVEILEKSSSISITRIRY------ 294
            .:::||....|....:|       .:|:|::.. :.||:.: |.::::..:.|....|:
Zfish   301 NSRLQKFFTRKGNKNVANGNAAAGSELEDVKTS-KIYSRGS-VVMVDEIINASPPNYRFPEAGLR 363

  Fly   295 ----------TTMRMIRNPRVSVNRRYTR-------------------NMKLD-YTQSKNQGIFR 329
                      |.:||.....::..:|..:                   |:..| .|:.|...:..
Zfish   364 VMVTNHFGPKTRLRMASRLIITERQRLVQSANGVETAVVDGKPDIENGNVPEDKSTEEKESELTT 428

  Fly   330 DFFLALRPIKCQAWKQAELLNRVLLLIRAPAVVICTLYIPLVDYEMEKHGWNKLLNAINVVVNPA 394
            .|.|   |..|        :||...||..|.::|....||    ...|..|.|
Zfish   429 PFRL---PDGC--------MNRTKWLISWPLLLILFFTIP----NCAKSRWEK------------ 466

  Fly   395 LSISIFLSFMHRKGNFLWYISLQNTLIYGASSFVL-TVPFAVFILFHARTDVPPSYHWVFTIMNL 458
                                       |...||:| ||..|||..|..         |:.||
Zfish   467 ---------------------------YFMLSFILSTVWIAVFSYFMV---------WMVTI--- 492

  Fly   459 TGSMFLIFLCATEIDTVLEVIGNILSIDDNYMGATVKAFTGNLGTLFANTAVAIHGYPKMAFASA 523
                                ||..|.|.|..||.|..|...::....|:..||..|...||.::.
Zfish   493 --------------------IGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNT 537

  Fly   524 IGGSFFTIVVTGNTVAYVRSLVGNRSEHHMEEYGEIAFIFLNMALFTILLW-----STTLGFFAR 583
            ||.:.|.|:|.......::::..|        ||.:..|.....|::::|.     .|.||....
Zfish   538 IGSNVFDILVGLGVPWALQTMAVN--------YGSVVMINSRGLLYSVVLLLGSVALTILGIHLN 594

  Fly   584 R-----SMGLYSIGLYVVYLLFVTLVHEEV 608
            .     .:|:|.:.||.|:|.|..::...|
Zfish   595 HWKLDFKLGVYVLLLYAVFLCFSIMIEYNV 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	23/111 (21%)
		Na_Ca_ex	458..603	CDD:279963	36/154 (23%)
slc24a4b	XP_002665845.2	TIGR00367	155..581	CDD:273039	107/545 (20%)
		Na_Ca_ex	156..298	CDD:279963	32/165 (19%)
		Na_Ca_ex	467..619	CDD:279963	49/191 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810