Protein Alignment unc-104 and HIK

DIOPT Version :9

• Sequence 1: NP_611155.3
• Gene: unc-104 / 36876
• FlyBaseID: FBgn0267002
• Length: 1739
• Species: Drosophila melanogaster
• Sequence 2: NP_173273.2
• Gene: HIK / 838418
• AraportID: AT1G18370
• Length: 974
• Species: Arabidopsis thaliana
• Alignment Length: 1131
• Identity: 254/1131 - (22%)
• Similarity: 413/1131 - (36%)
• Gaps: 405/1131 - (35%)

  Fly     4 VKVAVRVRPFNSREIARESKCIIEMAGATTAITNPKVPPNTSDSVKRFNFDYSYWSHDHHDADF- 67
            :.|.||:||.|.||:..:.:...|.....|.::.|:|....                 ||.:.|
plant    32 IVVTVRLRPMNKRELLAKDQVAWECVNDHTIVSKPQVQERL-----------------HHQSSFT 79

  Fly    68 --------STQSMVYKDIGEEMLQHSFDGYNVCIFAYGQTGAGKSYTMMGRQEEQQEGIIPMICK 124
                    |....||:|..:.:...:..|.|..|||||||.:||:|||.|..|:        ...
plant    80 FDKVFGPESLTENVYEDGVKNVALSALMGINATIFAYGQTSSGKTYTMRGVTEK--------AVN 136

  Fly   125 DLFTRIQDTETDDLKYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTDY 189
            |::..|  .:|.:..:::::|.:|||.|.||||||..:...|::.:.|..|..||.|.:....:.
plant   137 DIYNHI--IKTPERDFTIKISGLEIYNENVRDLLNSDSGRALKLLDDPEKGTVVEKLVEETANND 199

  Fly   190 QDIHDLIDEGNKARTVAATNMNETSSRSHAV--FTIFFTQRRHDLMTNLTTEKVSKISLVDLAGS 252
            ..:..||......|.|..|.:|:||||||.:  .||..|.|.:   ::.....::.::.||||||
plant   200 NHLRHLISICEAQRQVGETALNDTSSRSHQIIRLTIQSTHREN---SDCVRSYMASLNFVDLAGS 261

  Fly   253 ERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVASKKKNTKKADFIPYRDSALTWLLRENLG 317
            |||..:.|.||||:||.:||.||.||..||..|:.       .|::..||||||.||.:|:.:||
plant   262 ERASQSQADGTRLREGCHINLSLMTLTTVIRKLSV-------GKRSGHIPYRDSKLTRILQHSLG 319

  Fly   318 GNSKTAMIAAISPADINYDETLSTLRYADRAKQIVCKAVVNEDANAK-LIRELKEEIQKLRDLLK 381
            ||::||:|..:|||..:.:::.:||.:|:|||::...|.||...:.| |::.|::|:.:    |:
plant   320 GNARTAIICTLSPALAHVEQSRNTLYFANRAKEVTNNAHVNMVVSDKQLVKHLQKEVAR----LE 380

  Fly   382 AEGIEVQEEDELTKSTVIKSPTKSRNRNGSTTEMAVDQLQASEKLIAELNETWEEKLKRTEEIRV 446
            ||                      |...|.:||... ::|..|..|.||....::...:.||:|.
plant   381 AE----------------------RRTPGPSTEKDF-KIQQMEMEIGELRRQRDDAQIQLEELRQ 422

  Fly   447 QREAVFAEMGVAVKEDGITVGVFSPKKTPHLVNLNEDPNLSECLLYYIKEGLTRLGTHEANVPQD 511
            :.:      |...:..|:     :|.::|       ||.:.:||.|.:           |..|..
plant   423 KLQ------GDQQQNKGL-----NPFESP-------DPPVRKCLSYSV-----------AVTPSS 458

  Fly   512 IQLSGSHILKEHCTFENKNSTVTLLPHKDAIIYVNGRKLVEPEVLKTGSRVILGKNHVFRFTNPE 576
                           |||.                                 |.:|...|.|...
plant   459 ---------------ENKT---------------------------------LNRNERARKTTMR 475

  Fly   577 QARELRDKIETENEAENEVEKTDTQQVDWNFAQCELLEKQGIDLKAEMKKRLDNLEEQYKREKLQ 641
            |:.               :.::.|..               ..|..|::| |::|:||...|..:
plant   476 QSM---------------IRQSSTAP---------------FTLMHEIRK-LEHLQEQLGEEATK 509

  Fly   642 ADQQFEEQRKTYEARIDALQKQV-------EEQSMTMSMYSSYSPEDFHQEEDVYTNPMYESCWT 699
            |              ::.|||:|       ::.:.|::...:    :..:...|..:.|
plant   510 A--------------LEVLQKEVACHRLGNQDAAQTIAKLQA----EIREMRTVKPSAM------ 550

  Fly   700 AREAGLAAWAFRKWRYHQFTSLRDDLWGNAIFLKEANAISVELKKKVQFQFTLLTDTLYSPLPPE 764
            .:|.|                  |.:..|       .::|..||:::        ..|:|.
plant   551 LKEVG------------------DVIAPN-------KSVSANLKEEI--------TRLHSQ---- 578

  Fly   765 LASTVAPVHQEDEFGAPPVSKTLVAV--------EVTDTKNGATHHWSLEKLRYRLELMRQIYNV 821
             .||:|.:.::.|.....:.|.::::        |...|||   ||
plant   579 -GSTIANLEEQLESVQKSIDKLVMSLPSNISAGDETPKTKN---HH------------------- 620

  Fly   822 ESPPSSMLFDTSGMEALSGWISPPSQHPGQQAQLLPLEPPVESERGRLTLANLIP---SRQRLEL 883
                                      |..::.:||||.|...|.|.....:...|   |||.|:.
plant   621 --------------------------HQSKKKKLLPLTPSSASNRQNFLKSPCSPLSASRQVLDC 659

  Fly   884 MREMYHNEAEMSPTS----------------PDYNVESLTGGDPFYDRFPWFRMVGRSFIYLSNL 932
            ..|   |:|.....|                |....||   ||
plant   660 DAE---NKAPQENNSSAARGATTPQGSEKETPQKGEES---GD---------------------- 696

  Fly   933 LYPVPLVHKVAIVNERGDVRGYLRIAVQPVLDEESIDFNNGVKQSARLV------FNEDDAKPKY 991
                        |:.|....||.|.:...:...:.: |.|..:::.|.:      ..|..||.:|
plant   697 ------------VSSREGTPGYRRSSSVNMKKMQQM-FQNAAEENVRSIRAYVTELKERVAKLQY 748

  Fly   992 RALNEKDDVQRYIDNGGLDSKLEELEDVDSGRGIDSNSASECHENS-EEPGEHLQVGKEFTF--- 1052
                     |:.:    |..::.||| .:.|.|.    :.|..||: .|..|..||....||
plant   749 ---------QKQL----LVCQVLELE-ANDGAGY----SVENEENTIMEDEEQNQVAWHITFIEE 795

  Fly  1053 RVTVLQATGIGAEYADIFCQFNFLHR 1078
            |..:::...:        |..:.:||
plant   796 RQQIIELWHV--------CHVSIIHR 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-104	NP_611155.3	KISc_KIF1A_KIF1B	2..358	CDD:276816	123/364 (34%)
		KISc	3..358	CDD:214526	123/364 (34%)
		Kinesin_assoc	355..498	CDD:292801	31/143 (22%)
		FHA	475..574	CDD:238017	14/98 (14%)
		KIF1B	878..923	CDD:289208	12/60 (20%)
		DUF3694	1246..1347	CDD:289256
		PH_KIFIA_KIFIB	1602..1704	CDD:269939
		PH	1607..1700	CDD:278594
HIK	NP_173273.2	KISc_CENP_E	31..353	CDD:276825	122/357 (34%)
		Kinesin	37..353	CDD:278646	120/352 (34%)
		DUF3490	792..955	CDD:288820	5/30 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910