Protein Alignment unc-104 and AT3G10180

DIOPT Version :10

• Sequence 1: NP_611155.3
• Gene: unc-104 / 36876
• FlyBaseID: FBgn0267002
• Length: 1739
• Species: Drosophila melanogaster
• Sequence 2: NP_187629.3
• Gene: AT3G10180 / 820180
• AraportID: AT3G10180
• Length: 1273
• Species: Arabidopsis thaliana
• Alignment Length: 1210
• Identity: 302/1210 - (24%)
• Similarity: 485/1210 - (40%)
• Gaps: 315/1210 - (26%)

  Fly     1 MSSVKVAVRVRPFNSREIARESKCIIEMAGATTAITNP-KVPPNTSDSVKRFNFDYSYWSHDHHD 64
            |..:.|:||.||.:|.:                |.|:| |:   :|||:...|.....:..|...
plant     1 MERIHVSVRARPLSSED----------------AKTSPWKI---SSDSIFMPNHSSLAFEFDRIF 46

  Fly    65 ADFSTQSMVYKDIGEEMLQHSFDGYNVCIFAYGQTGAGKSYTMMGRQEEQQEGIIPMICKDLFTR 129
            .:......||:...:|::..:..|:|..:||||||.:||::||.|...|  .|:||:...|||..
plant    47 REDCKTVQVYEARTKEIVSAAVRGFNGTVFAYGQTNSGKTHTMRGSPIE--PGVIPLAVHDLFDT 109

  Fly   130 I-QDTETDDLKYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTDYQDIH 193
            | ||...:   :.:.:||:|||.|.:.|||.|::: .|::.|:...|.:|..|.:..|...|.:.
plant   110 IYQDASRE---FLLRMSYLEIYNEDINDLLAPEHR-KLQIHENLEKGIFVAGLREEIVASPQQVL 170

  Fly   194 DLIDEGNKARTVAATNMNETSSRSHAVFTIFFTQRR----HDLMTNLTTEKVSKISLVDLAGSER 254
            ::::.|...|.:..||||..|||||.:|.:....|:    ..:..:....:||.::|||||||||
plant   171 EMMEFGESHRHIGETNMNLYSSRSHTIFRMIIESRQKMQDEGVGNSCDAVRVSVLNLVDLAGSER 235

  Fly   255 ADSTGAKGTRLKEGANINKSLTTLGKVISALAEVASKKKNTKKADFIPYRDSALTWLLRENLGGN 319
            |..|||:|.|||||::|||||.|||.||..|:|...     .:...:|||||.||.:|:..||||
plant   236 AAKTGAEGVRLKEGSHINKSLMTLGTVIKKLSEGVE-----TQGGHVPYRDSKLTRILQPALGGN 295

  Fly   320 SKTAMIAAISPADINYDETLSTLRYADRAKQIVCKAVVNED-ANAKLIRELKEEIQKLRDLLKAE 383
            :.||:|..|:.|.|:.|||.|:|::|.||.::...|.|||. .:|.|::..|:||::||..||..
plant   296 ANTAIICNITLAPIHADETKSSLQFASRALRVTNCAHVNEILTDAALLKRQKKEIEELRSKLKTS 360

  Fly   384 GIEVQEEDELT-KSTVIKSPTKSRNRNGSTTEMAVDQLQASEKLIAELNETWEEKLKRTEEIRVQ 447
            ..:..||:.|. ::|::||..:                  .|::..||.   |||     :.:.|
plant   361 HSDHSEEEILNLRNTLLKSELE------------------RERIALELE---EEK-----KAQAQ 399

  Fly   448 REAVFAEMGVAVKEDGITVGVFSPKKTPHLVNLNEDPNLSECLLY----------YIKEG----- 497
            ||.|..|....:|                        |||..:|.          :.|:|
plant   400 RERVLQEQAKKIK------------------------NLSSMVLLSNRDEKREQDHFKKGKRRDT 440

  Fly   498 -----LTRLGTHEANVPQDIQLSGSHILKEHCTFENKNS---TVTLLPHKDAI---IY------- 544
                 |:|..|.|         ..|::|....:.|:..|   |..|||..:.:   :|
plant   441 WCIGKLSRDSTSE---------DQSNVLSRGSSLESARSERETGPLLPFSELVNEPLYNINEEDE 496

  Fly   545 --VNGRKLVEPEVLKTGS---RVILGKNHVFRFTNPEQARELRDKIETENEA------------E 592
              :.|  .:|..||....   .|...|....:..||.......|:|:.|.||            |
plant   497 DSIEG--TLEDSVLPDPCALVNVTSRKKPSIKQKNPVVVENELDRIQREYEALLLQYETERIISE 559

  Fly   593 NEVE---------------KTDTQQVDWNFAQCE------------LLEKQ------GIDL-KAE 623
            .::|               |....:|..| ..||            ||.||      .::| |:.
plant   560 IQIECLKVKLGEDGLSGDAKCKQSEVVGN-VHCEEHVVNLRDPEAILLIKQLQEKINMLELEKSS 623

  Fly   624 MKKRLDNLEEQYKREKLQADQQFEE-QRKTYEARID---ALQKQVEEQSMTMSMYSSYSPEDFHQ 684
            ..:.||:|......:.:.|.::|.| |.:.:.||.:   |.::.|.::|..:.:.:    |:|:.
plant   624 SNRNLDDLVMVATEQNICAREKFAEIQEEIHAAREEAQVAREQLVSKESEVIDVIN----ENFNS 684

  Fly   685 EEDVYT------------NPMYESCWTAREAGLAAWAFRKWRYHQFTSLRDDLWGNAIFLKEAN- 736
            ..:|.|            ....|:..:....||..:||.....|.||          :|:::::
plant   685 LVNVATEIEVLESEFQKYKASVETISSVMNEGLQDFAFFSPLIHDFT----------LFVRQSSE 739

  Fly   737 ----------AISVELKKK---VQFQFTLLTDTLYSPLPPELASTVAPVHQE-----------DE 777
                      .:...||||   |:.:..||.:....     |.|.:..::||           .|
plant   740 QHDSLINSYQTVQSSLKKKVLDVENEKLLLQEQCAG-----LQSQIEELNQEAQKHETSLKMLSE 799

  Fly   778 FGAPPVSKTLVAVEVTDTKNGATHHWSL----EKLRYRLELMR-QIYNVESPPSSMLFDTSGMEA 837
            ......|..|..:|..:...|:....||    |.||...|..: ::.:.||...:.:.|.:.:||
plant   800 HHESERSDLLSHIECLEKDIGSLSSSSLAKEKENLRKDFEKTKTKLKDTESKLKNSMQDKTKLEA 864

  Fly   838 LSGWISPPSQHPGQQAQLLPLE-PPVESERGRLTLANLIPSRQRLELMREMYHNEA---EMSPTS 898
            .........:....|..||..: ...||..|:...:.|:.......|..|....|.   ||..|.
plant   865 EKASAERELKRLHSQKALLERDISKQESFAGKRRDSLLVERSANQSLQEEFKQLEVLAFEMETTI 929

  Fly   899 PDY----------NVESLTGGDPFYDRFPWFRMVGRSFIYLSNLL--YPVPLVHKVAIVNERGDV 951
            ...          ..|:|...|.          :|.....|:..|  ....|.|   :.|:..::
plant   930 ASLEEELAAERGEKEEALCRNDG----------LGSEITDLTEKLEHSNTKLEH---LQNDVTEL 981

  Fly   952 RGYLRIAVQPVLDEESIDFNNGVKQSARLVFNEDDAKPKYRALNEKDDVQRYIDNGGLDSKLEEL 1016
            :..|.::..   |::.::.|  |||                .|.||:::..::.|..|:.:.|:.
plant   982 KTRLEVSSS---DQQQLETN--VKQ----------------LLEEKEELAMHLANSLLEMEEEKA 1025

  Fly  1017 --------------EDVDSGRGIDSNSASECHENSEEPGE 1042
                          |.:...:.|...|.|:  |.|||..|
plant  1026 IWSSKEKALTEAVEEKIRLYKNIQIESLSK--EMSEEKKE 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-104	NP_611155.3	KISc_KIF1A_KIF1B	2..358	CDD:276816	131/361 (36%)
		Kinesin_assoc	355..498	CDD:465047	37/164 (23%)
		FHA_KIF1	474..574	CDD:438757	25/137 (18%)
		YhaN	<575..>666	CDD:443752	30/140 (21%)
		KIF1B	878..924	CDD:463574	9/58 (16%)
		DUF3694	1199..1347	CDD:463599
		PH_KIFIA_KIFIB	1602..1704	CDD:269939
AT3G10180	NP_187629.3	KISc_CENP_E	4..327	CDD:276825	130/352 (37%)
		sbcc	<335..904	CDD:129705	132/649 (20%)
		SMC_prok_B	644..>1268	CDD:274008	91/475 (19%)