Protein Alignment unc-104 and AT2G21380

DIOPT Version :10

• Sequence 1: NP_611155.3
• Gene: unc-104 / 36876
• FlyBaseID: FBgn0267002
• Length: 1739
• Species: Drosophila melanogaster
• Sequence 2: NP_565510.1
• Gene: AT2G21380 / 816676
• AraportID: AT2G21380
• Length: 1058
• Species: Arabidopsis thaliana
• Alignment Length: 756
• Identity: 204/756 - (26%)
• Similarity: 335/756 - (44%)
• Gaps: 146/756 - (19%)

  Fly     3 SVKVAVRVRPFNSREIARESKCIIEMAGATTAITNPKVPPNTSDSVKRFNFDYSYWSHDHHDADF 67
            |:.|.||.||.:.||..|..: |:....|...:.|...|      :..:.||..:...
plant   104 SISVTVRFRPMSEREYQRGDE-IVWYPDADKMVRNEYNP------LTAYAFDKVFGPQ------- 154

  Fly    68 STQSMVYKDIGEEMLQHSFDGYNVCIFAYGQTGAGKSYTMMGRQEEQQEGIIPMICKDLFTRIQD 132
            ||...||....:.:::.:.:|.|..:||||.|.:||::||.|.|:  ..||||:..||:|:.||
plant   155 STTPEVYDVAAKPVVKAAMEGVNGTVFAYGVTSSGKTHTMHGDQD--FPGIIPLAIKDVFSIIQ- 216

  Fly   133 TETDDLKYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTDYQDIHDLID 197
             ||...::.:.|||:|||.|.:.|||:|..: |||:||.. .|.|||.:.:..|.........|.
plant   217 -ETTGREFLLRVSYLEIYNEVINDLLDPTGQ-NLRIREDS-QGTYVEGIKEEVVLSPGHALSFIA 278

  Fly   198 EGNKARTVAATNMNETSSRSHAVFTIFFTQRRH-DLMTNLTTEKVSKISLVDLAGSERADSTGAK 261
            .|.:.|.|.:.|.|..|||||.:||:......| |....:.   .|:::|:|||||| :..|...
plant   279 AGEEHRHVGSNNFNLMSSRSHTIFTLMIESSAHGDQYDGVI---FSQLNLIDLAGSE-SSKTETT 339

  Fly   262 GTRLKEGANINKSLTTLGKVISALAEVASKKKNTKKADFIPYRDSALTWLLRENLGGNSKTAMIA 326
            |.|.||||.|||||.|||.||..|.|        .|...:|:|||.||.||:.:|.|:...::|.
plant   340 GLRRKEGAYINKSLLTLGTVIGKLTE--------GKTTHVPFRDSKLTRLLQSSLSGHGHVSLIC 396

  Fly   327 AISPADINYDETLSTLRYADRAKQIVCKAVVNEDANAK-LIRELKEEIQKLR------------- 377
            .::||..:.:||.:||::|.|||:|...|..|:..:.| ||::.::||..|:
plant   397 TVTPASSSTEETHNTLKFASRAKRIEINASRNKIIDEKSLIKKYQKEISTLKVELDQLRRGVLVG 461

  Fly   378 ----DLLK-----AEG-------IEVQEE---------DELTKSTVIK-----------SPTKSR 406
                :||.     .||       :|.:||         .:|||..::.           :|..||
plant   462 VSHEELLSLKQQLQEGQVKMQSRLEEEEEAKAALMSRIQKLTKLILVSTKNSIPGYLGDTPAHSR 526

  Fly   407 NRN--------------------GSTTEMAVDQLQASEKLIAELNETWEEKLKRTEEIRVQREAV 451
            :.:                    .||..:|.|..::|.|...| |.....:.:.|:.:...
plant   527 SISAGKDDKLDSLLLDSDNLASPSSTLSLASDARRSSSKFKDE-NSPVGSRAELTQGVMTP---- 586

  Fly   452 FAEMGVAVKEDGITVG--VFSPKKTPHLVNLN-EDPNLSECLLYYIKEGLTRLGTHEANVPQDIQ 513
             .||.:.|::..:..|  .|.......||:.: .||..|:..:..::..:........::.|.|.
plant   587 -DEMDLLVEQVKMLAGEIAFGTSTLKRLVDQSMNDPENSKTQIQNLENDIQEKQRQMKSLEQRIT 650

  Fly   514 LSGSHILKEHCTFENKNSTVTLLPHKDAIIYVNGRKLVEPEVLKTGSRVILGKNHVFRFTNPEQA 578
            .||...:....:.|.:...:.|:...:       .|..|.|::...:|::              .
plant   651 ESGEASIANASSIEMQEKVMRLMTQCN-------EKSFELEIISADNRIL--------------Q 694

  Fly   579 RELRDKIETENEAENEV----EKTDTQQVDWNFAQCELLEKQGIDLKAEMKKRLDNLEEQYKREK 639
            .:|:.|....||...:|    ::..:|:.  ..:.|:::.::.:|   |:||::.:.|.:.::.|
plant   695 EQLQTKCTENNELHEKVHLLEQRLSSQKA--TLSCCDVVTEEYVD---ELKKKVQSQEIENEKLK 754

  Fly   640 LQADQQFEEQRKTYEARIDALQKQVEEQSMTMSMYSSYSPE 680
            |:..|..||:.   ..|:.. ||..||.|....:.|:.:.|
plant   755 LEHVQSVEEKS---GLRVQN-QKLAEEASYAKELASAAAIE 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-104	NP_611155.3	KISc_KIF1A_KIF1B	2..358	CDD:276816	130/355 (37%)
		Kinesin_assoc	355..498	CDD:465047	40/215 (19%)
		FHA_KIF1	474..574	CDD:438757	15/100 (15%)
		YhaN	<575..>666	CDD:443752	20/94 (21%)
		KIF1B	878..924	CDD:463574
		DUF3694	1199..1347	CDD:463599
		PH_KIFIA_KIFIB	1602..1704	CDD:269939
AT2G21380	NP_565510.1	KISc_CENP_E	104..421	CDD:276825	128/348 (37%)
		Mplasa_alph_rch	<609..>813	CDD:275316	40/213 (19%)
		PTZ00121	<737..997	CDD:173412	18/62 (29%)
		mRING-HC-C3HC5_CGRF1-like	1009..1046	CDD:438311