Protein Alignment unc-104 and Klp67A

DIOPT Version :10

• Sequence 1: NP_611155.3
• Gene: unc-104 / 36876
• FlyBaseID: FBgn0267002
• Length: 1739
• Species: Drosophila melanogaster
• Sequence 2: NP_523992.2
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Alignment Length: 777
• Identity: 213/777 - (27%)
• Similarity: 347/777 - (44%)
• Gaps: 187/777 - (24%)

  Fly     2 SSVKVAVRVRPFNSREIARESKCIIEMAGATTAITNP------------KVPPNTSDSVKRFN-- 52
            :::||||||||:|.||:.::.:.||::...:..:.:|            |.|  ..|..||.|
  Fly     7 TNIKVAVRVRPYNVRELEQKQRSIIKVMDRSALLFDPDEEDDEFFFQGAKQP--YRDITKRMNKK 69

  Fly    53 ----FDYSYWSHDHHDADFSTQSMVYKDIGEEMLQHSFDGYNVCIFAYGQTGAGKSYTMMGRQEE 113
                ||..:      |.|.|.|.: :::....::....:|||..:|.||.|||||::||:|  .|
  Fly    70 LTMEFDRVF------DIDNSNQDL-FEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLG--SE 125

  Fly   114 QQEGIIPMICKDLFTRIQDTETDDLKYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYV 178
            ...|:..:..:|||.:|| .::|..|:.|.|||:|:|.|.|.:||.  ..|.|::||.. .|..|
  Fly   126 AHPGLTYLTMQDLFDKIQ-AQSDVRKFDVGVSYLEVYNEHVMNLLT--KSGPLKLREDN-NGVVV 186

  Fly   179 EDLSKLAVTDYQDIHDLIDEGNKARTVAATNMNETSSRSHAVFTIF--FTQRRHDLMTNLTTEKV 241
            ..|....:...:::..::..||..||...|:.|..||||||:|.:.  .|:|:.|      |::.
  Fly   187 SGLCLTPIYSAEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRITERKTD------TKRT 245

  Fly   242 SKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVASKKKNTKKADFIPYRDS 306
            .|:|::||||||||.||...|.|.||||:|||||..||..|:.||:         ....||||||
  Fly   246 VKLSMIDLAGSERAASTKGIGVRFKEGASINKSLLALGNCINKLAD---------GLKHIPYRDS 301

  Fly   307 ALTWLLRENLGGNSKTAMIAAISPADINYDETLSTLRYADRAKQI-------VCKAVVNEDANAK 364
            .||.:|:::||||.:|.|:|.:|.:.:.|::|.:||:||.|||:|       |.|:.:..:...|
  Fly   302 NLTRILKDSLGGNCRTLMVANVSMSSLTYEDTYNTLKYASRAKKIRTTLKQNVLKSKMPTEFYVK 366

  Fly   365 LIRELKEEIQKLRD---LLKAEGIEVQEE-----DELTKST------------------VIKSPT 403
            .|.|:..|.::|::   .|:|:..:::..     |.|...|                  |:...:
  Fly   367 KIDEVVAENERLKERNKALEAKATQLERAGNSGFDPLELKTWYSKIDAVYAAARQLQEHVLGMRS 431

  Fly   404 KSRNRNGSTTEMAVDQLQASEKLIAELNETWEEKLKR--------TEEIRVQREAV---FAEMGV 457
            |.:|.|...|  ...:|:...||:.......:|..:|        |.::...:|.:   .::|.:
  Fly   432 KIKNINYRQT--LKKELEEFRKLMCVDQRVCQEDFRRFANYMSTLTSQMEKYKEELPSWLSKMEI 494

  Fly   458 AVKEDGITVGVFSPKKTPHLVNLNEDPNLS---ECLLYYIK-EGLTRLGTHEANVPQDIQLSGSH 518
            |.::               |.:|..:.|.|   :.|:.|:| :.|            ::||:..:
  Fly   495 AYQD---------------LESLKREVNKSKAYQILIVYVKYKDL------------ELQLTKQN 532

  Fly   519 ILKEHCTFEN----KNSTVTLLPHKDAIIYVN--------GRKLVEPEVLKTGSRVILGKNHVFR 571
            |...|....|    :|..:.....:.|...:|        |:||. ||:.....|::    ...|
  Fly   533 IFNNHVNAINQELVENLDLMRKSFRTACEVLNQTYDRLEDGQKLT-PEIEAVFERLL----RKMR 592

  Fly   572 FTNPE------QARELRDKIETENEAENEVEKTDTQQVDWNFAQCELLEKQGIDLKAEMKKRL-- 628
            |.:.|      :...|...:...:.|:.|.|.|           |        .|.|..|||.
  Fly   593 FADSEANTKMAEMNPLAVPVALRSSAQEEEEPT-----------C--------SLTASAKKRQRQ 638

  Fly   629 -----DNLE---EQYKREKLQADQQFEEQRKTYEARIDALQKQV------EEQSMTMSMYSS 676
                 |:|.   |.:..:..::|.  ||..:|::...:..:.||      ...|.|.|..|:
  Fly   639 AAQSDDDLHLSMEDFDSQDTESDS--EELHRTFKRPRNLNETQVLGPCSSSSSSSTSSSSSA 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-104	NP_611155.3	KISc_KIF1A_KIF1B	2..358	CDD:276816	140/382 (37%)
		Kinesin_assoc	355..498	CDD:465047	31/183 (17%)
		FHA_KIF1	474..574	CDD:438757	24/115 (21%)
		YhaN	<575..>666	CDD:443752	21/112 (19%)
		KIF1B	878..924	CDD:463574
		DUF3694	1199..1347	CDD:463599
		PH_KIFIA_KIFIB	1602..1704	CDD:269939
Klp67A	NP_523992.2	KISc_KIP3_like	8..346	CDD:276821	137/367 (37%)