Protein Alignment unc-104 and pav

DIOPT Version :10

• Sequence 1: NP_611155.3
• Gene: unc-104 / 36876
• FlyBaseID: FBgn0267002
• Length: 1739
• Species: Drosophila melanogaster
• Sequence 2: NP_477025.1
• Gene: pav / 38515
• FlyBaseID: FBgn0011692
• Length: 887
• Species: Drosophila melanogaster
• Alignment Length: 837
• Identity: 197/837 - (23%)
• Similarity: 315/837 - (37%)
• Gaps: 242/837 - (28%)

  Fly     4 VKVAVRVRPFNSREIARESKCIIEMAGATTAITNPK-------VPPNTSDSVKRFNFDYSYWSHD 61
            |.|..||||..|    ......:.:..:||...||:       .|.|.:....::.|.:.:
  Fly    37 VNVFCRVRPLQS----DADLTSLRVKNSTTIALNPQDQLLQHHKPHNGAQREVQYIFKHVF---- 93

  Fly    62 HHDADFSTQSMVYKDIGEEMLQHSFDGYNVCIFAYGQTGAGKSYTMMGRQEEQQEGIIPMICKDL 126
            ..||   ||..||..:.:.::::...|.|..:|.||.||:||:|||.|..  :..||:|.....|
  Fly    94 QPDA---TQQDVYAAVAQPLVENLLKGRNSLLFTYGVTGSGKTYTMTGNL--RHRGIMPRCLDVL 153

  Fly   127 FTRIQDTET-------------------------------------------------------- 135
            |..|.|.:.
  Fly   154 FRTISDYQAKKFVFKPDKLNGFEILSEEDALLERQHEMNQRFAGSGRFAFRHKDSDPEIASQASV 218

  Fly   136 ---------DDLKYSVEVSYMEIYCERVRDLLN----PKNKGNLRVREHPLLGPYVEDLSKLAVT 187
                     :|..|||.|:|:|||...|.|||.    .|...:..:||......:|..::::.|.
  Fly   219 EPIPLLGLDEDNMYSVFVTYIEIYNNSVYDLLEDSGIQKTLQSKIIREDANRHMFVHGVTEVEVK 283

  Fly   188 DYQDIHDLIDEGNKARTVAATNMNETSSRSHAVFTIFFTQRRHDLM--------TNLTTEKVSKI 244
            ..:|..::...|.|.:.:..|.:|..|||||:||.|...|...|..        .|:|   ||::
  Fly   284 TVEDALEVFQMGQKRKRMGHTVLNAESSRSHSVFNIRLVQAPTDSQGENVVQDRQNIT---VSQL 345

  Fly   245 SLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAE---VASKKKNTKKADFIPYRDS 306
            ||||||||||:..|...|.||:|..|||.||.||...:..|.|   .||.....||   :|||||
  Fly   346 SLVDLAGSERSSRTKNTGVRLREAGNINNSLMTLRTCLEYLRENQLAASNGLAPKK---VPYRDS 407

  Fly   307 ALTWLLRENLGGNSKTAMIAAISPADINYDETLSTLRYADRAKQI-VCKAV-VNED-----ANAK 364
            .:|.:.:....|..:.:||..|:|...:|||.:..:::|:..::: :.:|. :.:|     ...|
  Fly   408 KITHMFKNYFDGEGQVSMIVCINPRIEDYDENMQVMKFAEMTQEVQIARATPMKQDLGLTPGRRK 472

  Fly   365 LIRELKEEIQKLRDLLKAEGIEVQEEDELTKSTVIKSPTKSRNRNGSTTEMAVDQLQASEKLIAE 429
            ..:..|..:..|.:|...|..:::.:..|..|.....|.           ..:|..:|..| |.|
  Fly   473 ANKLFKIAVNNLNELGIPEAKDLEVDVGLVYSLGPDFPA-----------YEMDSPEAQIK-IRE 525

  Fly   430 LNETWEEKLKRTEEIRVQREAVFAEMGVAVKEDGITVGVFSPKKTPHLVNLNEDPNLSECLLYYI 494
            |....|:::::.:::|...:         :|.|..         ...|:||:.| ||
  Fly   526 LMHYLEQRIEKRKKLRANLD---------IKCDSF---------RQMLMNLDRD-NL-------- 563

  Fly   495 KEGLTRLGTHEANVPQDIQLSGSHILKEHCTFENKNSTVTLLPHKDAIIYVNGRKLVEPEVLKTG 559
             :..|.|.:.:|...|:...|.:        .|.|     :..|:.:|..:|.
  Fly   564 -QLRTELASLKAVYKQERDRSAA--------LEKK-----VRIHESSIDVLNN------------ 602

  Fly   560 SRVILGKNHVFRFTNPEQARELRDKI-ETEN---EAENEVEKTDTQ-------QVDWNFAQCEL- 612
               .|.|..       .|..||..|: |.||   :.|:|.||...:       :.|.|..:.||
  Fly   603 ---TLSKQE-------RQIEELTFKLNEKENMLTQKEHEKEKQKKKFSSKLAVESDKNKREFELK 657

  Fly   613 LEKQGIDLKAEMKKRLDNL---------EEQYKREKLQADQQF--EEQRKTYEARIDALQKQVEE 666
            |.:|.:.|:..|:.:.:.|         |:.....:.|:.:..  |:.|..|.||       .||
  Fly   658 LREQRVKLQERMRIKDEKLRLVSNILQSEDLPSLPRSQSSENILNEKDRGAYTAR-------TEE 715

  Fly   667 QSMTMSMYSSYSPEDFHQEEDVYTNPMYESCWT------AREAGLAAWAFRKWRYHQ 717
            .|:..:            ..|:|..|.:.:...      :|.||      .||..|:
  Fly   716 SSVPAT------------RTDIYATPRHGAAAANNRHRRSRSAG------DKWLEHR 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-104	NP_611155.3	KISc_KIF1A_KIF1B	2..358	CDD:276816	121/442 (27%)
		Kinesin_assoc	355..498	CDD:465047	26/148 (18%)
		FHA_KIF1	474..574	CDD:438757	18/99 (18%)
		YhaN	<575..>666	CDD:443752	27/113 (24%)
		KIF1B	878..924	CDD:463574
		DUF3694	1199..1347	CDD:463599
		PH_KIFIA_KIFIB	1602..1704	CDD:269939
pav	NP_477025.1	KISc_KIF23_like	35..450	CDD:276819	120/431 (28%)
		PRK03918	<522..>687	CDD:235175	46/228 (20%)
		MKLP1_Arf_bdg	734..840	CDD:465166	6/27 (22%)