Protein Alignment unc-104 and klp8

DIOPT Version :10

• Sequence 1: NP_611155.3
• Gene: unc-104 / 36876
• FlyBaseID: FBgn0267002
• Length: 1739
• Species: Drosophila melanogaster
• Sequence 2: NP_594675.1
• Gene: klp8 / 2542849
• PomBaseID: SPAC144.14
• Length: 511
• Species: Schizosaccharomyces pombe
• Alignment Length: 490
• Identity: 143/490 - (29%)
• Similarity: 231/490 - (47%)
• Gaps: 92/490 - (18%)

  Fly     2 SSVKVAVRVRPFNSREIARESKCI--IEMAGATTAITNPK------VPPNTSDSVKRFNFDYSYW 58
            ::|:|.|||||.:.||:::.::.:  ::....|..||.||      ...|..:..:.|.||..:.
pombe     4 ANVRVIVRVRPKSLRELSKSAEDLLSVDSHNKTVTITPPKHGLKHSRHKNRVNGPRTFAFDECFA 68

  Fly    59 SHDHHDADFSTQSMVYKDIGEEMLQHSFDGYNVCIFAYGQTGAGKSYTMMGRQEEQQEGIIPMIC 123
            .......:.|.|..||:..|..:::...:|:|.|...|||.|.||:|:::|.:  .|.||||.|.
pombe    69 PSAPESKNLSGQEDVYESTGPLLVKSILEGFNSCFITYGQKGTGKTYSVVGLR--GQPGIIPHIS 131

  Fly   124 KDLFTRIQDTETDDLK-------YSVEVSYMEIYCERVRDLLNPKNKGN------LRVREHPLLG 175
            :.:|     .|.|.||       .:|.:|..||..|...|||.|....:      :.|::..|.|
pombe   132 ESIF-----EEIDKLKKKSPNTTITVSISLAEIIEETPYDLLQPNVNSSHTPGETVFVQKDSLTG 191

  Fly   176 PYVEDLSKLAVTDYQDIHDLIDEGNKARTVAATNMNETSS------RSHAVFTIFFTQRRHDLMT 234
            .::..||:..|...|:|...:       .:||.|:....|      :.|:||::...||..|..|
pombe   192 YHLHGLSEFEVGSAQEIDAFL-------RLAAKNIRTELSDISGVRKGHSVFSLVVQQRIIDPKT 249

  Fly   235 NLTTEKVSKISLVDLA----GSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVASKKKNT 295
            ..:.:|.|::.::|||    ||:|.:|..:     .|.::.||||:.|.:||:||   .|||.:.
pombe   250 RHSLKKASRLQIIDLASFSKGSQRNESISS-----FESSSNNKSLSVLNRVIAAL---TSKKNDV 306

  Fly   296 KKADFIPYRDSALTWLLRENLGGNSKTAMIAAISPADINYDETLSTLRYADRAKQIVCKAVVNED 360
                .|||:||.||.||::.||||.:|.|:..:||.|  :|:|.|.|||::.|::|  |.:.|
pombe   307 ----LIPYKDSVLTTLLQDALGGNCRTIMLTCVSPCD--FDDTFSALRYSEAARRI--KNISN-- 361

  Fly   361 ANAKLIRELKEEIQKLRDLLKAEGIEVQEEDELTK-STVIKSPTKSRNRNGSTTEMAVDQLQASE 424
            .|.|                  |......|.||.. .|.::|..:...|:...::..:
pombe   362 INCK------------------EAYSTNNEGELDDILTTLESDREQLRRHEEHSQKLL------- 401

  Fly   425 KLIAELNETWEEKLKRTEEIRVQREAVFAEMGVAV 459
            |.|.|:...:||::...|.   |..|:.|.:.:||
pombe   402 KFIEEIRNDYEERIHALES---QNSALKAHLRLAV 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-104	NP_611155.3	KISc_KIF1A_KIF1B	2..358	CDD:276816	122/386 (32%)
		Kinesin_assoc	355..498	CDD:465047	21/106 (20%)
		FHA_KIF1	474..574	CDD:438757
		YhaN	<575..>666	CDD:443752
		KIF1B	878..924	CDD:463574
		DUF3694	1199..1347	CDD:463599
		PH_KIFIA_KIFIB	1602..1704	CDD:269939
klp8	NP_594675.1	KISc	5..354	CDD:276812	119/376 (32%)