DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15617 and ush1c

DIOPT Version :9

Sequence 1:	NP_611151.1	Gene:	CG15617 / 36871	FlyBaseID:	FBgn0034151	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	XP_009296312.1	Gene:	ush1c / 564412	ZFINID:	ZDB-GENE-060312-41	Length:	586	Species:	Danio rerio

Alignment Length:	213	Identity:	45/213 - (21%)
Similarity:	78/213 - (36%)	Gaps:	82/213 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GMEVTGGIDQFEPLTIVNVSPTGLAKRGGMRVGDEITQINDVPALEMTFNEALQMFRKNSRYVRV 108
            |:.::.|..:...:.:.||.|..|:...|::|||:|.::|.|....::..||:::. |:||.:.:
Zfish   226 GISISSGPTKKPGIYVSNVKPGSLSAEVGLQVGDQIVEVNGVEFTNLSHQEAVRVL-KSSRSLTI 289

  Fly   109 YV---RGDD-----------DAPGEEDWTCDCWFKPRKPWRRDFTPIQWTFPWNDRRKPVYKESN 159
            .|   .|.:           :|..|.|             |::..          .:|.|..|:|
Zfish   290 TVLTGAGSELFMTDEERLAVEARHELD-------------RQELM----------HQKKVALETN 331

  Fly   160 CFMVPSKMEEKIRARR----------------------AATSAVHKKDE---------------- 186
              .:..:.:||.|.|:                      ||....||:.|
Zfish   332 --KIVKEQQEKERQRKMEISQKAAEEEERYRKEMERIEAAEKKHHKEWEDDWGSKEKKKSVSPAA 394

  Fly   187 ---LAPHTRSLTPTPRPK 201
               ..|.|| |.|:|:||
Zfish   395 SPSPPPPTR-LAPSPKPK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15617	NP_611151.1	PDZ_signaling	30..111	CDD:238492	19/69 (28%)
ush1c	XP_009296312.1	harmonin_N	2..80	CDD:259819
		PDZ_signaling	85..165	CDD:238492
		PDZ_signaling	212..292	CDD:238492	18/66 (27%)
		RILP-like	317..>379	CDD:304877	13/73 (18%)
		PDZ_signaling	447..534	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900