DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15617 and grip2b

DIOPT Version :9

Sequence 1:	NP_611151.1	Gene:	CG15617 / 36871	FlyBaseID:	FBgn0034151	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	XP_021325304.1	Gene:	grip2b / 562290	ZFINID:	ZDB-GENE-070705-172	Length:	1086	Species:	Danio rerio

Alignment Length:	229	Identity:	58/229 - (25%)
Similarity:	92/229 - (40%)	Gaps:	55/229 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KIRVPKYDSDAFDNVAYELQMTYTLETDCRIMSFYDAMWGMEVTGGIDQFEPLTIVNVSPTGLAK 69
            |:::.| |.|..|.......:.||:|     :..|....|:.::|..:.|:|:.|..::..|||:
Zfish   639 KLKIRK-DEDNSDEQESSGSIIYTVE-----LKRYGGPLGITISGTEEPFDPIIISGLTKRGLAE 697

  Fly    70 R-GGMRVGDEITQINDVPALEMTFNEALQMFRKNSRYVRVYVRGDDDAPGE-------------- 119
            | |.:.|||.|..||.|.......:||:.:.:.....|.:.::...|:|.|
Zfish   698 RTGAIHVGDRILAINSVSLKGKPLSEAIHLLQMAGETVTLKIKKQADSPDEKNKENDLENDLSDN 762

  Fly   120 EDWTCDCWFKPRKPWRRDFTPIQWTFPWNDRRKPVYKESNCFMVPSKME----EKIRARRAATSA 180
            ||               :.|..|.|...:|    :| .:....|.|.||    ..|.|..::..|
Zfish   763 ED---------------EMTDSQKTNKLSD----IY-STTIPSVDSAMESWDGSGIDAGYSSQGA 807

  Fly   181 -VHKKDELA--PH------TRSLTPTP-RPKNQP 204
             :|:...:|  ||      .|:.||.| |.||.|
Zfish   808 FIHQAAGIALHPHEWRNTKQRNSTPPPTRRKNYP 841

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15617	NP_611151.1	PDZ_signaling	30..111	CDD:238492	22/81 (27%)
grip2b	XP_021325304.1	PDZ_signaling	45..127	CDD:238492
		PDZ	144..232	CDD:214570
		PDZ_signaling	245..328	CDD:238492
		PDZ_signaling	462..548	CDD:238492
		PDZ_signaling	561..643	CDD:238492	1/3 (33%)
		PDZ_signaling	659..740	CDD:238492	24/85 (28%)
		Peptidase_S41	672..>841	CDD:321971	48/188 (26%)
		PDZ_signaling	970..1050	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910