DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf6 and chia.2

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_998414.1	Gene:	chia.2 / 406338	ZFINID:	ZDB-GENE-040426-2014	Length:	470	Species:	Danio rerio

Alignment Length:	427	Identity:	106/427 - (24%)
Similarity:	183/427 - (42%)	Gaps:	89/427 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIERDSHKAVSLNQQLDLDLG-KGLYRTV 96
            ||:.:.|..:.|:||.....::|.|  |.:|.|.:|.|..       .|:.:..:.. :.||:..
Zfish    25 CYFTNWSQYRPGIGKYTPANVDPFL--CTHLFYAFAMINH-------ANELITYEWNDETLYKAF 80

  Fly    97 TRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYLELLESPTGRTRFVNTVYSLVKTYGFDGLD 161
            ..||...|:::.||:|||         ......::..::.|...|..|:.:....::||||||:|
Zfish    81 NELKNTNPHLRTLLAVGG---------WNFGSTQFSIMVSSAANRQTFIQSSIKFLRTYGFDGMD 136

  Fly   162 VAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEEHKEQFTALLRDVKNAFRPD------ 220
            :.|::|.::        ||                  ..|.|::||.|.:::..|:..:
Zfish   137 LDWEYPGSR--------GS------------------PPEDKQRFTLLCKELLEAYEAEGKATGR 175

  Fly   221 -NLLLSTTVLP---NVNSSLFYDIPAVVNYLDFVNLGTFDFF-TPQRNPEVADYAAPIYELSERN 280
             .|:||..|..   .::..  |:|..:..||||:|:.|:||. |.:|   ...:.:|:|:.|:..
Zfish   176 RRLMLSAAVSAGKGTIDDG--YEIAEIAKYLDFINIMTYDFHGTWER---FTGHNSPLYQGSKDE 235

  Fly   281 PE---FNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDSGDTGVPPVKDVKDEAPVGGNTQV 342
            .:   ||....::||..|..|..|:.:|.|||||.::||......|.|    ....|..|..|:.
Zfish   236 GDLVYFNTDYAMRYWRDNGTPVEKLRMGFATYGRTFRLTSSDTSVGAP----ASGPASAGTYTRE 296

  Fly   343 PGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGDNGIWVSFEDPDTAA 407
            .|.:|:.|:|..|......::.....|             ||.:       |..||.|:..::..
Zfish   297 AGFWSYYEICGFLEGTTVQWIDDQKVP-------------YATK-------NSEWVGFDTKESYE 341

  Fly   408 DKAGYVRTENLGGVALFDLSYDDFRG-LCTNEKYPIL 443
            .|..|::.:..||..::.|..|||.| .|....:|::
Zfish   342 TKVRYLKDKKFGGAFVWALDLDDFAGQFCGQGNHPLM 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	106/427 (25%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	100/410 (24%)
chia.2	NP_998414.1	GH18_chitolectin_chitotriosidase	23..385	CDD:119351	106/427 (25%)
		Glyco_18	24..363	CDD:214753	100/410 (24%)
		CBM_14	423..468	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592071
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940