DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf6 and Idgf5

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster

Alignment Length:	447	Identity:	218/447 - (48%)
Similarity:	295/447 - (65%)	Gaps:	23/447 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LC--LASIQA--SKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIE 71
            ||  ||..|:  ::||       .|||:||:.|||:||..::.:.|||||||||::||||||||:
  Fly    14 LCSFLAFFQSTYAEVG-------KLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGID 71

  Fly    72 RDSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYLELLE 136
            ..::|..||:..|..|  :..||.:|.|::|||:|:.|||||||:|:..:..|..  :|||.|||
  Fly    72 AVTYKIKSLDPSLTND--RQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADS--DKYLRLLE 132

  Fly   137 SPTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEE 201
            ....|..|..:|.:.:...||||:|:|||||||:||........:|...:..||..| |||||||
  Fly   133 QSEHRKSFQASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSS-VDEKSEE 196

  Fly   202 HKEQFTALLRDVKNAFRPDNLLLSTTVLPNVNSSLFYDIPAVVNYLDFVNLGTFDFFTPQRNPEV 266
            |:|||..||.::::..|....||:.::||:|::.||.|:|.|::.:|||||||:||.||:|:|:|
  Fly   197 HREQFATLLEELQSDLRRGGQLLTVSMLPHVSAELFIDVPKVLSNVDFVNLGTYDFQTPERDPKV 261

  Fly   267 ADYAAPIYELSERNPEFNVAAQVKYWLRNNCPAS--KINVGVATYGRPWKLTDDSGDTGVPPVKD 329
            ||...|:|.:.:|:|..||..||:||:......|  |::|||.:|||.|.:|.:||.||.||:..
  Fly   262 ADLPTPLYAMYDRDPSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTRNSGITGYPPIPA 326

  Fly   330 VKDEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAP-LIKVQDPAKRFGSYAYRAADKKGD 393
            ....||.|..|..||:.||||:|.||..|.    :....| |.||.||.||||.|||||||.:|:
  Fly   327 ANGAAPPGRQTVTPGLLSWPEICDLLQQQP----QDREVPHLRKVGDPTKRFGIYAYRAADDQGE 387

  Fly   394 NGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCTNEKYPILRAIKYRL 450
            ||:||.:|||.|||.|||:|..:.|||||..|||.|||||.|..||:||||:||::|
  Fly   388 NGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQCAGEKFPILRSIKFKL 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	210/422 (50%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	196/400 (49%)
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	210/422 (50%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	196/401 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469727
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D227150at33208
OrthoFinder	1	1.000	-	-		FOG0008541
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850