DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf6 and Cht10

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	455	Identity:	128/455 - (28%)
Similarity:	206/455 - (45%)	Gaps:	91/455 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KVGAPQLPKKHL--------------------VCYYDSASFVKEGLGKLVIDELEPALQFCDYLV 64
            |...||.|..||                    :||:.:.::.::|:|:...|::...|  |.:::
  Fly   936 KPPTPQTPSSHLRPTYPTEKPVPKPRDSHYKVICYFTNWAWYRKGIGRFTPDDINTEL--CTHVI 998

  Fly    65 YGYAGIERDSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPN 129
            ||:|.:  |..:.|........|:....|..||.||.|  .:|:.|::||..|.:.|
  Fly   999 YGFAVL--DYSELVLRTHDSWADVENNFYTRVTSLKSK--GIKVSLALGGWNDSQGD-------- 1051

  Fly   130 KYLELLESPTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSI 194
            ||..|:.||..|:|||......::.|||:|||:.|::|.....:.:.|
  Fly  1052 KYSRLVRSPMARSRFVRHALEFIEKYGFEGLDLDWEYPVCWQTECNKG----------------- 1099

  Fly   195 VDEKSEEHKEQFTALLRDVKNAFRPDNLLLSTTVLPN---VNSSLFYDIPAVVNYLDFVNLGTFD 256
                |.|.|:.|||.::::..||||..|:|||.|.|:   :::.  ||||.:..|.|::.:.|:|
  Fly  1100 ----STEEKDGFTAWVQELSEAFRPRGLMLSTAVSPSRKIIDAG--YDIPQLSRYFDWIAVMTYD 1158

  Fly   257 FFTPQRNPEVADYAAPIYELSERNPE-FNVAAQVKYWLRNNCPASKINVGVATYGRPWKL--TDD 318
            |.  ....:...:.||:|...:.:.| |||...:.||:....|:.|:.:|:..||:.:.|  |:.
  Fly  1159 FH--GHWDKKTGHVAPLYHHPDDDFEYFNVNYSINYWMEKGAPSQKLVMGIPLYGQSFTLENTNS 1221

  Fly   319 SGDTGVPPVKDVKDEAP--VGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFG 381
            ||       .:.|..||  .|..|:..|..::.|:|..:..|....          |.|...|.|
  Fly  1222 SG-------LNAKAPAPGEAGEFTRAAGFLAYYEICERVNRQGWQV----------VHDEFGRMG 1269

  Fly   382 SYAYRAADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCTNEKYPILRAI 446
            .|||:...       |||::.||....|:..||:..|||..::.|..|||:..|.|..:|:|..|
  Fly  1270 PYAYKGTQ-------WVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKNRCGNGVHPLLTEI 1327

Fly 447 446
Fly 1328 1327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	124/445 (28%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	115/425 (27%)
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753	114/406 (28%)
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351	122/424 (29%)
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463777
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840