DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Idgf6 and Idgf4

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	287/449 - (63%)
Similarity:	350/449 - (77%)	Gaps:	8/449 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IKALAIVSLCLASIQASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGY 67
            :|..|:.||.:.|:...::.|  ....||:||||..|||:|||.||::.:||||||:|.:|||||
  Fly     1 MKLYALFSLLVGSLAIGQISA--AGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGY 63

  Fly    68 AGIERDSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYL 132
            |||...|:|.||.|::||||||..|:|.||.||||||.:|:||||||||| .:|.:    .||||
  Fly    64 AGINPSSNKLVSNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKD-TVDPE----NNKYL 123

  Fly   133 ELLESPTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDE 197
            .||||...|..|:|:.:||||||||||||:.||||||||||||..||..||||||:||||.:|||
  Fly   124 TLLESSNARIPFINSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDE 188

  Fly   198 KSEEHKEQFTALLRDVKNAFRPDNLLLSTTVLPNVNSSLFYDIPAVVNYLDFVNLGTFDFFTPQR 262
            |:|||||.||||:|::|||||||..:|..:||||||||||:|:||::|.||:|||.|:||.||:|
  Fly   189 KAEEHKEAFTALVRELKNAFRPDGYILGLSVLPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPER 253

  Fly   263 NPEVADYAAPIYELSERNPEFNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDSGDTGVPPV 327
            |.||||:.||||||:||||||||..|||||..|..||:|||||:|||||.||||.|||.||:|||
  Fly   254 NNEVADFPAPIYELNERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPV 318

  Fly   328 KDVKDEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKG 392
            .:....||.|..||:||:.|||||||.|||..|.:||||:.||.||.||.|||||||||:||..|
  Fly   319 AEADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSG 383

  Fly   393 DNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCT-NEKYPILRAIKYRL 450
            :||:||.:|||||||.||.||:.|.|||:|:.|||:|||||.|| ::|:||||.:|.:|
  Fly   384 ENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	280/420 (67%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	266/397 (67%)
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	280/420 (67%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	266/397 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469714
Domainoid	1	1.000	504	1.000	Domainoid score	I1179
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	1	1.000	-	-		H122304
Inparanoid	1	1.050	533	1.000	Inparanoid score	I2817
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D227150at33208
OrthoFinder	1	1.000	-	-		FOG0008541
OrthoInspector	1	1.000	-	-		mtm9660
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	11	10.900