DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf6 and RGD1309110

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_006233175.1	Gene:	RGD1309110 / 295352	RGDID:	1309110	Length:	440	Species:	Rattus norvegicus

Alignment Length:	455	Identity:	106/455 - (23%)
Similarity:	197/455 - (43%)	Gaps:	126/455 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIERDSHKAVSLNQQLDLDLGKGLYRT 95
            |:||:::....:..:..:.:|:::|.|  |.:|:|.:|||..:::   ::.::.|||    .|:.
  Rat    41 LMCYFNNWPQYQPDVRGMKLDDIDPCL--CTHLIYSFAGIWENNN---TMTKRKDLD----DYKE 96

  Fly    96 VTRLKRKYPNVKILLSVG------GDKDIELDKDAKELPNKYLELLESPTGRTRFVNTVYSLVKT 154
            ...||::...:|.|||:|      |               .::.::.:|..|..|:.:|...::.
  Rat    97 FNDLKKRNNKLKTLLSIGCWNFEAG---------------LFITMVSTPESRHTFITSVRKFLRK 146

  Fly   155 YGFDGLDVAWQFP---KNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEEHKEQFTALLRDVKNA 216
            ||||||::|||:|   .:.||..|                             .||.|.::::.|
  Rat   147 YGFDGLNLAWQYPGCYGSPPKDKH-----------------------------LFTILTQEIRKA 182

  Fly   217 FRPD------NLLLSTTVLPNVNSSL--FYDIPAVVNYLDFVNL------GTFDFFTPQRNPEVA 267
            |..:      :.|:.|..|..|.|.:  .|.:|.:...||::.:      |::|.:|.:.:|.
  Rat   183 FEKEVSKNKKSRLIITAALAGVISPIQFGYHVPQLSQSLDYIQVMTYDLHGSWDGYTGENSPL-- 245

  Fly   268 DYAAPIYELSERNPEFNVAA--QVKY----WLRNNCPASKINVGVATYGRPWKLTDDS-GDTGVP 325
             |.:|        .|..|.|  .:||    |........|:.||...||..:.|:|.: .:.|.|
  Rat   246 -YKSP--------AETGVKAFYNIKYTMHNWKNKGVSPEKLIVGFPAYGHTFILSDSTKTEIGAP 301

  Fly   326 PVKDVKDEAPVGGN----TQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYR 386
            ..:        ||:    |:..|.:::.|:||.|.|       ||    |:|.:.|::. .||:.
  Rat   302 SNR--------GGHPGPYTKKTGFWAYYEICAFLKN-------GA----IQVWNAAQQV-PYAFH 346

  Fly   387 AADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRG-LCTNEKYPILRAIKYRL 450
            ..:       ||.:::..:...||.:::..|.||..::.:..||:.| .|....:|:...:|..|
  Rat   347 GNE-------WVGYDNVKSFHIKAQWLKNNNFGGAMIWAIGMDDYTGSFCDQGPFPLTSTLKNAL 404

Fly 451 450
Rat 405 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	105/453 (23%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	99/431 (23%)
RGD1309110	XP_006233175.1	GH18_chitolectin_chitotriosidase	41..404	CDD:119351	105/453 (23%)
RGD1309110	XP_006233175.1	Glyco_18	43..382	CDD:214753	98/429 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350368
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740