DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf6 and Chit1

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001073157.1	Gene:	Chit1 / 289032	RGDID:	1305646	Length:	464	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	126/473 - (26%)
Similarity:	218/473 - (46%)	Gaps:	119/473 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IVSLCLASI---------QASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYL 63
            :.||.||.:         .|:|          |.||:.:.:..:.|..:.:..:::|.|  |.::
  Rat     2 VQSLALAGVTTLLMIQWGSAAK----------LFCYFTNWAQYRSGAARFLPRDVDPNL--CTHV 54

  Fly    64 VYGYAGIERDSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELP 128
            :|.:||:.......|..|.:|       .|:.:..||::.|.:|.||:|||         .....
  Rat    55 IYAFAGLNNHQVSTVEPNDEL-------FYQELNSLKKRNPKLKTLLAVGG---------WSFGT 103

  Fly   129 NKYLELLESPTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDS 193
            .|:.:::.:.:.|..|||:..|.::|:||||||:.|::|.::                    |..
  Rat   104 QKFTDMVATASTRQTFVNSALSFLRTHGFDGLDLDWEYPGSR--------------------GSP 148

  Fly   194 IVDEKSEEHKEQFTALLRDVKNAFRPD------NLLLSTTVLP----NVNSSLFYDIPAVVNYLD 248
            .||      ||:||||::|:..||:.:      :.||.|..:|    :|::.  |::..:|..||
  Rat   149 AVD------KERFTALIQDLAKAFQEEARASGKSRLLLTAAVPTGRGHVDAG--YEVDKIVQSLD 205

  Fly   249 FVNLGTFDFFTPQRNPEVADYAAPIYEL---SERNPEFNVAAQVKYWLRNNCPASKINVGVATYG 310
            |:||..:||.:..  .:...:.:|:|:.   :.::.|.||.|.|..||:...||||:.:|:..||
  Rat   206 FINLMAYDFHSSW--DKTTGHNSPLYKRQGETGKDAEKNVDAAVTLWLQKGTPASKLMLGMPAYG 268

  Fly   311 RPWKLTDDSGDTGVPPVKDVKDEAPV------GGNTQVPGIYSWPEVCALLPNQNNAYLKGANAP 369
            |.:.|. .|.|:||        .||.      |..|:..||..:.|||:....|
  Rat   269 RSFTLA-SSSDSGV--------GAPATGPGAPGPYTKEKGILVYFEVCSWKGKQ----------- 313

  Fly   370 LIKVQDPAKRFGSYAYRAADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRG- 433
              :::|....:.|        :|:.  ||.|:|.::...||.||:.:.|||..::.|..|||:|
  Rat   314 --RIEDQKVPYVS--------QGNQ--WVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGS 366

  Fly   434 LCTNEKYPILRAIKYRLT 451
            .|...:||::|.:...|:
  Rat   367 FCNEGQYPLIRTLHQELS 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	119/439 (27%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	111/416 (27%)
Chit1	NP_001073157.1	GH18_chitolectin_chitotriosidase	24..383	CDD:119351	119/438 (27%)
Chit1	NP_001073157.1	ChtBD2	416..463	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350392
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.940