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Protein Alignment Idgf6 and CHIA

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_970615.2	Gene:	CHIA / 27159	HGNCID:	17432	Length:	476	Species:	Homo sapiens

Alignment Length:	441	Identity:	110/441 - (24%)
Similarity:	197/441 - (44%)	Gaps:	98/441 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIERDSHKAVSLNQQLDLDLGKGLYRT 95
            |.||:.:.:..:.|||:.:.|.::|.|  |.:|:|.:||.:.:....:..|...       ||:.
Human    24 LTCYFTNWAQYRPGLGRFMPDNIDPCL--CTHLIYAFAGRQNNEITTIEWNDVT-------LYQA 79

  Fly    96 VTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYLELLESPTGRTRFVNTVYSLVKTYGFDGL 160
            ...||.|...:|.||::||       .:....|  :..::.:|..|..|:.:|...::.|.||||
Human    80 FNGLKNKNSQLKTLLAIGG-------WNFGTAP--FTAMVSTPENRQTFITSVIKFLRQYEFDGL 135

  Fly   161 DVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEEHKEQFTALLRDVKNAFRPD----- 220
            |..|::|.::        ||                  ..:.|..||.|:::::.||..:
Human   136 DFDWEYPGSR--------GS------------------PPQDKHLFTVLVQEMREAFEQEAKQIN 174

  Fly   221 --NLLLSTTV---LPNVNSSLFYDIPAVVNYLDFVNLGTFDF------FTPQRNPEVADYAAPIY 274
              .|:::..|   :.|:.|.  |:||.:..|||::::.|:|.      :|.:.        :|:|
Human   175 KPRLMVTAAVAAGISNIQSG--YEIPQLSQYLDYIHVMTYDLHGSWEGYTGEN--------SPLY 229

  Fly   275 EL---SERNPEFNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDSGDTGV-PPVKDVKDEAP 335
            :.   :..|...||...:.||..|..||.|:.||..|||..:.|::.| :||: .|....   .|
Human   230 KYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPS-NTGIGAPTSGA---GP 290

  Fly   336 VGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGDNGIWVSF 400
            .|...:..||:::.|:|..|   .|...:|.:||    |:.     .|||:       ..:||.:
Human   291 AGPYAKESGIWAYYEICTFL---KNGATQGWDAP----QEV-----PYAYQ-------GNVWVGY 336

  Fly   401 EDPDTAADKAGYVRTENLGGVALFDLSYDDFRG-LCTNEKYPILRAIKYRL 450
            ::..:...||.:::....||..::.:..|||.| .|...|:|::..:|..|
Human   337 DNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKAL 387

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.