DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf6 and cht-2

DIOPT Version :9

Sequence 1:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_495798.2	Gene:	cht-2 / 174363	WormBaseID:	WBGene00011757	Length:	626	Species:	Caenorhabditis elegans

Alignment Length:	403	Identity:	89/403 - (22%)
Similarity:	164/403 - (40%)	Gaps:	101/403 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 YLVYGYAGIERDSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKE 126
            :||:.:..::.|.      :.:|:.|..|.....|..:..::|::|:|.:|||.::
Worm    56 HLVFAFFVVDSDG------SVKLEGDAAKARLEHVKEVASRHPDLKLLYAVGGWEN--------- 105

  Fly   127 LPNKYLELLESP-TGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFS 190
              ::|..:|.:. :.|:..::....::|.|||||:|:.|::|                     .:
Worm   106 --SQYFSVLTADHSRRSILISNFVKVIKEYGFDGVDIDWEYP---------------------VT 147

  Fly   191 GDSIVDEKSEEHKEQFTALLRDVKNAFRP------DNLLLS-------TTVLPNVNSSLFYDIPA 242
            |.::  |.:...:..:..|:|:::|..|.      .:.|:|       ..:.|.      ||:..
Worm   148 GGAV--EGTPADRRNYVNLMRELRNELRDLESETGKSYLISFAGAAGHWVLKPG------YDLQQ 204

  Fly   243 VVNYLDFVNLGTFDFFTPQRNPEVADYAAPIYELSERNPE-----FNVAAQVKYWLRNNCPASKI 302
            ::.|.||||:.::|:|....:...| |..|...|....|:     .||.|.:|.:........||
Worm   205 LMKYCDFVNVMSYDYFGAWASKWGA-YTGPPAPLQFAMPKKFSGRMNVHATMKDYSCQIKATDKI 268

  Fly   303 NVGVATYGRPWK-------LTDDSGDTGVPPVKD-VKDEAPVGGNTQVPGIYSWPEVCALLPNQN 359
            |:||..|||.||       .|||...|......: .|.|   ||:.|      |.::........
Worm   269 NMGVPFYGRFWKNVGDAVDSTDDMWRTATATNSEGTKFE---GGDVQ------WRDLHEKFDTTK 324

  Fly   360 NAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALF 424
            ..:..|:..|.|.:.: .|.|                 |.:|:.::...|..|:...|:|||.::
Worm   325 TKFHSGSKTPFIWLSE-QKTF-----------------VGYENAESLKHKVDYIVENNIGGVMIW 371

  Fly   425 DLSYDDFRGLCTN 437
            .:.:||.:|...|
Worm   372 AIDFDDDQGTLLN 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	89/403 (22%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	85/393 (22%)
cht-2	NP_495798.2	Glyco_18	33..376	CDD:214753	85/393 (22%)
		GH18_chitinase-like	35..376	CDD:299167	85/393 (22%)
		ChtBD1_GH18_2	418..469	CDD:211315
		ChtBD1_GH18_2	496..547	CDD:211315
		ChtBD1_GH18_2	567..618	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770