Protein Alignment Picot and FEN2

DIOPT Version :10

• Sequence 1: NP_725600.1
• Gene: Picot / 36865
• FlyBaseID: FBgn0024315
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_009957.1
• Gene: FEN2 / 850394
• SGDID: S000000623
• Length: 512
• Species: Saccharomyces cerevisiae
• Alignment Length: 496
• Identity: 99/496 - (19%)
• Similarity: 169/496 - (34%)
• Gaps: 171/496 - (34%)

  Fly    40 RYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDGEFAWS 104
            :|::.::..:|..|||:                   ||..|  |.:....|:.:.:
Yeast    44 QYWINYVDRVGFTNAYI-------------------SGMKE--DLKMVGNDLTVSN--------- 78

  Fly   105 SALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGL---- 165
                    :.|..||::..:|..::........:|.:     ..||            |||
Yeast    79 --------TVFMIGYIVGMVPNNLMLLCVPPRIWLSF-----CTFA------------WGLLTLG 118

  Fly   166 ----------CAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGL 220
                      ||:||.|.|.|......||.:|..|...:|.. :.:|::.|:  |.:.|| .||.
Yeast   119 MYKVTSFKHICAIRFFQALFESCTFSGTHFVLGSWYKEDELP-IRSAIFTGS--GLVGSM-FSGF 179

  Fly   221 LAEYGFD--------GGWPSIFYV-FGIVGTVWSIAFLIF---------VHEDPSSHPTIDEREK 267
            :....|.        .||..:|.: |.|...:....|:.|         |.:...:....:|:|.
Yeast   180 MQTSIFTHLNGRNGLAGWRWLFIIDFCITLPIAIYGFIFFPGLPDQTSAVSKFSMTRYIFNEQEL 244

  Fly   268 KYINDSLWGTDVVKSPPIPFKAIIKSLP-----FYAILFAHMGHNYGYETLMTELPTYMKQVLRF 327
            .|....|...|  :|..:.:..|.:.|.     .:::::...|.|.|:.:..|.......|....
Yeast   245 HYARRRLPARD--ESTRLDWSTIPRVLKRWHWWMFSLVWVLGGENLGFASNSTFALWLQNQKYTL 307

  Fly   328 SLKSN--------GLLSSL---------PYLAMWLFSMFISVV---------ADWMISSKRFSHT 366
            :.::|        |::|:|         |....|..|:|||:|         ||.:.....||
Yeast   308 AQRNNYPSGIFAVGIVSTLCSAVYMSKIPRARHWHVSVFISLVMVIVAVLIRADPLNPKVVFS-- 370

  Fly   367 ATRKLINSIGQYGPGVALIAASYTG-----------C-----DRALTLAILTIGVGLNGGIYSGF 415
                     .||..|||     |.|           |     :||:.||.:.:   .:|.:.:.:
Yeast   371 ---------AQYLGGVA-----YAGQAVFFSWANIICHADLQERAIVLASMNM---FSGAVNAWW 418

  Fly   416 KINHL--DLTPRFAGFLMSITNCSANLAGLLAPIAAGHLIS 454
            .|...  |:.|:|.      ..|.|    |||...:..::|
Yeast   419 SILFFASDMVPKFE------RGCYA----LLATAISSGIVS 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	99/495 (20%)
FEN2	NP_009957.1	MFS_FEN2_like	32..450	CDD:340885	99/496 (20%)