DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Picot and Slc17a4

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001258143.1	Gene:	Slc17a4 / 679784	RGDID:	1584758	Length:	495	Species:	Rattus norvegicus

Alignment Length:	493	Identity:	164/493 - (33%)
Similarity:	260/493 - (52%)	Gaps:	28/493 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RDGHVLVWNQRNLHESLEQQPQR-CFATRYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKS 76
            |:|.:.  |..||:.:.||..:: |.:.|:.:.|:|.|...:.|..:.|:|:||.||||.||
  Rat    10 REGGIP--NDSNLNMTQEQSFKKGCCSLRHGLAFILHLCNFSVYTQQMNLSIAITAMVNTTA--- 69

  Fly    77 GEAEEYDDECGDRDIPIDDSQD-----------GEFAWSSALQGYILSSFFYGYVITQIPFGILA 130
              |..:.:...:|  |..||||           ..:.|:..:||.:|||..||..:..||.|.:|
  Rat    70 --ASSHANASIER--PTTDSQDFWNETLQESKAPVYDWTPEIQGILLSSLNYGSFLAPIPTGYVA 130

  Fly   131 KKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNE 195
            ..:|:...:|.|:|::||....:|:||. .||..|..:|.|||:.:..::...::|.|||.||.|
  Rat   131 GVFGAKYVVGLGLLVSSVLTLFIPLAAE-AGVALLIVLRVIQGMSQVMVLTGQYSMWAKWAPPLE 194

  Fly   196 RSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHP 260
            ||::.....:|:..||.:.:...|||.:   ..|||.|||:||.:|....:.:...|::||.:||
  Rat   195 RSQLITIAASGSMLGTFLVLIAGGLLCQ---ALGWPYIFYIFGGIGCACCLLWFPLVYDDPQNHP 256

  Fly   261 TIDEREKKYINDSLWGTDVVKSPPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVL 325
            .|...||:||..||...|......:|.||::||||.:||:.::....:...|:|...|||:..||
  Rat   257 FISTGEKRYIMCSLAQEDCSLGWSLPIKAMVKSLPLWAIVVSYFCEYWLLFTIMAYTPTYISSVL 321

  Fly   326 RFSLKSNGLLSSLPYLAMWLFSMFISVVADWMISSKRFSHTATRKLINSIGQYGPGVALIAASYT 390
            :.:|:.:|:||:||::...:..:...::||:::|.........|||..::|.......|:...:.
  Rat   322 QANLRDSGILSALPFMFGCVCIILGGLLADFLLSRNILRLVTIRKLFTALGVLVSSGILVPLPWV 386

  Fly   391 GCDRALTLAILTIGVGLNGGIYSGFKINHLDLTPRFAGFLMSITNCSANLAGLLAPIAAGHLISD 455
            ....:.|:|.|.:.........||..||.||:.||:||||..:....:.|||.:||..||..||.
  Rat   387 SSSLSTTMAFLVLSSVFASLCDSGALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFISQ 451

  Fly   456 PSKPMMGQWQIVFFIAAFVYIICGTFYNIFGSGERQYW 493
            .|:  .| |:.||.:||.:.::...||.|||..|.|.|
  Rat   452 DSE--FG-WRNVFLLAAAIDVVGLLFYLIFGRAEVQDW 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	155/464 (33%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	128/384 (33%)
Slc17a4	NP_001258143.1	MFS_SLC17	40..479	CDD:340876	150/452 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342533
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840