DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Picot and slc37a1

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001007440.1	Gene:	slc37a1 / 492798	ZFINID:	ZDB-GENE-041114-151	Length:	529	Species:	Danio rerio

Alignment Length:	517	Identity:	101/517 - (19%)
Similarity:	184/517 - (35%)	Gaps:	129/517 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 ATRYFVTFMLF----LGMANAYVMRT----NMSVAIVA--MVNHTAIKSGEAEEYDDECGDRDIP 92
            |..:.:||:|:    |......::::    |.|.|:.|  .::.::.:.|...|:|  |..:  |
Zfish    22 AFTFALTFLLYTSFHLSRKPISIVKSELHKNCSHAVEAPTEISSSSQQPGHHPEFD--CSWK--P 82

  Fly    93 IDDSQDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVF------AF 151
            .|.:.      ...|.|.:..||.:.|.|.....||:.::.....:|..|||.:.:|      .:
Zfish    83 FDRNN------YKQLLGAMDYSFLFAYAIGMFLSGIIGERLPIRLYLTVGMLTSGLFTCLFGLGY 141

  Fly   152 LVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMP 216
            :..:.:.|..::...|...:|..|...:|.|    :..|.....|..:.....:....|.|
Zfish   142 IYDIHSLGFYIFVQVANGLVQTTGWPSVVTC----IGNWFGKGRRGLIMGLWNSHTSVGNI---- 198

  Fly   217 LSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDP---------SSHPTIDEREKK---- 268
            |..|:|.|.....|...|.|.|::.....:....|:.|.|         ||.|:..:..|.
Zfish   199 LGSLIAGYYVSSNWGLSFIVPGVIIAAMGVICFFFLIEHPNDLKTASTQSSAPSSQKFHKSCNGV 263

  Fly   269 ------YI------NDSLWGTDVVKSP-------PIPFKAIIKS--------------LP----- 295
                  |:      ....|.|:::...       |:....::||              :|
Zfish   264 NGHKDLYLQYKPGAKAQSWDTELLLGQESIGVCVPVQQVVVVKSEAEPSAISFMGALRIPGVVEF 328

  Fly   296 FYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMISS 360
            ...:|||.:   ..| |.:..||.|:.:......|..|.||:|..:...:..:...|::|.|  .
Zfish   329 SLCLLFAKL---VSY-TFLFWLPLYITKAAHLDAKKAGDLSTLFDVGGIVGGILAGVISDKM--H 387

  Fly   361 KRFSHTATRKLI--------NSIGQYGPGV---------ALIAASYTGCDRALTLAILTIGVGLN 408
            ||.:..|...|:        :.:.|:|.|.         .|:...|         |::|..|..:
Zfish   388 KRATTCAVMLLLAAPMLYGFSMMSQFGLGPTIGMLLVCGGLVNGPY---------ALITTAVSAD 443

  Fly   409 GGIYSGFKINHLDLTPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFI 470
            .|.:...|.|     .|....:.:|.:.:.::...:.|:.|| |:|...      |..||::
Zfish   444 LGTHKSLKGN-----ARALSTVTAIIDGTGSVGAAVGPLLAG-LLSARG------WDQVFYM 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	100/514 (19%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	86/445 (19%)
slc37a1	NP_001007440.1	UhpC	92..501	CDD:332119	85/437 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582653
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840