DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Picot and MFS9

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	510	Identity:	182/510 - (35%)
Similarity:	272/510 - (53%)	Gaps:	39/510 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RDGHVLVWNQRNLHESLEQQP---QRCFATRYFVTFMLFLGMANAYVMRTNMSVAIVAMV-NHTA 73
            ::|..|....:|.:|..|.:|   :.....||.|..:.|.|..|.|.:|.|:|||||||. |.|.
  Fly     8 KNGKHLEQVHQNNNEITESEPLTWRFWRKQRYIVVLLAFFGFFNVYSLRVNLSVAIVAMTENRTV 72

  Fly    74 IKSGEAEEYDDECGDRDIPIDDSQDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRF 138
            .             |.|..:...||  |.|.|..:|.|||||||||::||...|.:..|.|....
  Fly    73 F-------------DADGNVSYQQD--FPWDSKQKGLILSSFFYGYILTQFLGGYIGTKIGGNIV 122

  Fly   139 LGYGMLINSVFAFLVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAV 203
            .|.|:...::...|.|:|| ...:.....||.|:|..||...|..||:.|:|.||.|||||.:..
  Fly   123 FGTGIGSTAILTLLTPMAA-SHSLEMFLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMASIA 186

  Fly   204 YAGAQFGTIISMPLSGLLA-EYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREK 267
            :||...||:::||.||.|| :|    ||.|:|||||.:|.:|.|.:|:||...|.......:.|.
  Fly   187 FAGNYAGTVVAMPCSGFLATKY----GWESVFYVFGTIGVIWYITWLVFVKAGPELDRFCSKEEC 247

  Fly   268 KYINDSLW--GTDVVKSPPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLK 330
            .||..::.  |:..||.   |::||..|:|||||:.:|...|:|:.||:|:||::::..|.|.|.
  Fly   248 DYIQKTIGYVGSKHVKH---PWRAIFTSMPFYAIMASHFSENWGFYTLLTQLPSFLRDTLNFDLG 309

  Fly   331 SNGLLSSLPYLAMWLFSMFISVVADWMISSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRA 395
            ..|:||::|||||.:.......:|||:.....::.|..|:..|........|.::..:|. .|..
  Fly   310 KTGILSAVPYLAMGILLAVSGYLADWLQVKGIWTTTQVRRNFNCGAFLAQTVFMMLTAYL-LDPT 373

  Fly   396 LTLAILTIGVGLNGGIYSGFKINHLDLTPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPM 460
            .::..|||.|||....:|||.:||||:.|:.|..||.|.|..|.:.|:::|:..|:::::.:.
  Fly   374 WSVVSLTIAVGLGAFAWSGFAVNHLDIAPQHASVLMGIGNTFATIPGIVSPLLTGYVVTNQTS-- 436

  Fly   461 MGQWQIVFFIAAFVYIICGTFYNIFGSGERQYW-DNPE----DDEQKPALQTTVT 510
             .:|:|:|||:|.:|::....|..:.||:.|.| ..||    :.|:|..||.|.|
  Fly   437 -DEWRIIFFISAGIYLVGCVIYWFYCSGDLQEWAKTPEQKAQEAEEKAQLQLTQT 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	169/468 (36%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	142/387 (37%)
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	170/465 (37%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	161/444 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.860