DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Picot and slc37a2

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_998179.2	Gene:	slc37a2 / 406287	ZFINID:	ZDB-GENE-040426-1949	Length:	494	Species:	Danio rerio

Alignment Length:	501	Identity:	110/501 - (21%)
Similarity:	179/501 - (35%)	Gaps:	123/501 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECG-----------DRD--- 90
            |:.:.|:.|:...:.::.|..:|:          :||    :....|.           |.|
Zfish    21 RFSILFLTFVFYTSYHLSRKPISI----------VKS----QLHRNCSNVVHPANLNITDNDTWC 71

  Fly    91 --IPIDDSQDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLV 153
              :|.|...      ...|.|.:.:.|...|.:.....||..::.....:|..|||::.:|..|.
Zfish    72 DWVPFDGKN------YQNLFGVLDNCFLVAYAVGMFFSGIFGERLPLRYYLSTGMLLSGLFTALF 130

  Fly   154 PVAARGGG-------VWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGT 211
                 |.|       :|..|.|:.:.||.:....|...|.:..|....:|..:.....:....|.
Zfish   131 -----GLGFYWQIHSLWYYCLVQALNGLVQTTGWPAVVACVGNWFGKGKRGFIMGVWNSHTSVGN 190

  Fly   212 IISMPLSGLLAEYGFDGGWPSIFYVFG-IVGTVWSIAFLIFVH--ED-----PSSHPTIDER--- 265
            |    |..|:|.......|...|.|.| |:.:...|.||..|.  ||     |..|..::|.
Zfish   191 I----LGSLIAGVYVSSAWGLSFIVPGIIIASTGVICFLFLVERPEDVNCTAPQHHERVEEEPLL 251

  Fly   266 EKKYINDSLWG--TDVVKSP------PIPFKAIIKSLP-----FYAILFAHMGHNYGYETLMTEL 317
            .....|:.::.  |.....|      .|.|...:: :|     .:.:|||.:   ..| |.:..|
Zfish   252 RNSSTNEEIFNSHTSTAVEPVEDHSEAISFCGALR-IPGVVEFSFCLLFAKL---VSY-TFLYWL 311

  Fly   318 PTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMISSKRFSHTATRKLI--------NS 374
            |.|:..|..|..|..|.||:|..:...|..:...:|:|:  :..|.|......:|        |.
Zfish   312 PLYIANVAHFDPKKAGDLSTLFDVGGILGGIVAGLVSDY--TGGRASTCCAMLIIAAPMLFLYNK 374

  Fly   375 IGQYG----PGV-----ALIAASYTGCDRALTLAILTIGVGLNGGIYSGFKINHLDLTPRFAGFL 430
            |||.|    .|:     ||:...|         |::|..|..:.|.:...:.|     .|....:
Zfish   375 IGQNGLPTTVGMLLWCGALVNGPY---------ALITTAVSADLGTHESLRGN-----SRALSTV 425

  Fly   431 MSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFF--IAAFV 474
            .:|.:.:.::...:.|:.|| |||...      |..||:  |||.|
Zfish   426 TAIIDGTGSIGAAVGPLLAG-LISPTG------WNNVFYMLIAADV 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	109/500 (22%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	98/425 (23%)
slc37a2	NP_998179.2	UhpC	20..470	CDD:332119	110/501 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582661
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840