DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Picot and CG12490

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_611722.2	Gene:	CG12490 / 37623	FlyBaseID:	FBgn0034782	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	152/458 - (33%)
Similarity:	239/458 - (52%)	Gaps:	27/458 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDGEFAWS 104
            |:....::||.:...::.|.|:.|::|||.|             .|..:.:.|       |:.|:
  Fly    14 RHVQALLIFLNITTVFIGRLNVGVSVVAMTN-------------AETTNPNFP-------EYDWT 58

  Fly   105 SALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAVR 169
            .|.:.||.||||:||::||...|.|.|::|....:.:|:.::.|.:.|.|:....||....|.:|
  Fly    59 EAEKSYIFSSFFWGYILTQFIGGYLCKRFGVKSVMFWGVFVSGVCSALTPLFIGFGGWQAYCGIR 123

  Fly   170 FIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDGGWPSIF 234
            .:.||.:|.:.||.|..||||.||.||:|:||..:.|.:.|.:.:|.|||::|:...  |||.|.
  Fly   124 VVMGLAQGLVFPCIHHHLAKWSPPAERNRLGALSHTGMECGNVSAMFLSGMIAKSAI--GWPGIS 186

  Fly   235 YVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSL-WGTDVVKSP-PIPFKAIIKSLPFY 297
            ||...:...|...:.:|..::......|.:.|..||..|| ...|..|:. |:|:.||..|.||.
  Fly   187 YVSAGLAFAWCAIWFVFAADNAVESRYITQEELHYIESSLKHNEDYHKTVIPVPWMAIWTSAPFL 251

  Fly   298 AILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMISSKR 362
            |:........:|..||..::||||..||...:|||...|:||:||||:.|....::||.:::..|
  Fly   252 ALTLTRCCATWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNR 316

  Fly   363 FSHTATRKLINSIGQYGPGVALIAASYTGCD-RALTLAILTIGVGLNGGIYSGFKINHLDLTPRF 426
            .|.||.||..||:..:.|...||...:...: :.|.:|::||.||:|.|...|..:|.:||:|..
  Fly   317 LSLTALRKTFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNH 381

  Fly   427 AGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAFVYIICGTFYNIFGSGERQ 491
            |..||.|.|.:..:..::.|:..|.::.:...  ..:|||||.|||.::.:..:.|..||:...|
  Fly   382 ASILMGILNTAVTVVPIVTPLIVGVIVHEDDN--RAEWQIVFIIAAVLFFVGNSVYLYFGTAVSQ 444

  Fly   492 YWD 494
            .||
  Fly   445 PWD 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	151/457 (33%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	135/387 (35%)
CG12490	NP_611722.2	2A0114euk	14..450	CDD:129972	152/458 (33%)
CG12490	NP_611722.2	MFS	54..438	CDD:119392	135/387 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451979
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D46132at33392
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	10	9.900