DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Picot and MFS15

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster

Alignment Length:	493	Identity:	194/493 - (39%)
Similarity:	272/493 - (55%)	Gaps:	54/493 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 FATRYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDGEF 101
            |..|:....::|.|:|.||.:|.|:|||||||.:..|             .:.|.|       ||
  Fly    24 FGVRHLQCILVFFGLAVAYSLRVNLSVAIVAMTDRNA-------------SNPDFP-------EF 68

  Fly   102 AWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLC 166
            .|:.:.:.|:|||||:|||:||||.|.|:..||:...|.||:||.|..|.|.|..|..||...:.
  Fly    69 DWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALLTPFCAVNGGWTVVV 133

  Fly   167 AVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDGGWP 231
            .:|.:|||.:|.|.|.||..|:||.|..||.|:....|:|:||||::.:.:||.:|....  |||
  Fly   134 VLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVMLSVSGYIASSSL--GWP 196

  Fly   232 SIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSLW-------GTDVVKSPPIPFKA 289
            |.||:.|.||.|||..:|......|:.||||...|:::|..|..       |.:....||.|:..
  Fly   197 STFYIPGCVGIVWSFVWLYLCSSTPAQHPTITPNERRFIESSGQARRPSDAGREEQPRPPTPWWR 261

  Fly   290 IIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFS-MFISVV 353
            |..|:||..::.||..:|:|:.||:||:||:||.||...:|:||.||:|||.||.|.: :||
  Fly   262 IFTSVPFLVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSALPYFAMILLTCVFI--- 323

  Fly   354 ADWMISSKRFSHTA-----TRKLINSIGQYGPGVALIAASYTGCDRA---LTLAILTIGVGLNGG 410
              |:..:.:...|.     :||..|::|.:.|.:|||...|.....|   |.:.:||..|..|..
  Fly   324 --WLSDTLKQRGTVIPLGFSRKFFNTLGMWLPMLALIGLGYITEGEANVRLAIGLLTAAVATNSA 386

  Fly   411 IYSGFKINHLDLTPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAFVY 475
            .|.||.:||:||:|.:||.||.||||:||...:|||:..|.::.|.:.|  .||:||||..||||
  Fly   387 TYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWDETNP--AQWRIVFFFTAFVY 449

  Fly   476 IICGTFYNIFGSGERQYWDNPEDDEQKPALQTTVTTSP 513
            .|....:.:||....|.|::      :|   ||.|.||
  Fly   450 FIGNLLFMLFGRTRVQPWNS------RP---TTRTPSP 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	186/475 (39%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	165/400 (41%)
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	188/473 (40%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	182/456 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451965
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D46132at33392
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	10	9.900