DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Picot and Slc17a9

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	XP_038961483.1	Gene:	Slc17a9 / 362287	RGDID:	1311940	Length:	448	Species:	Rattus norvegicus

Alignment Length:	381	Identity:	89/381 - (23%)
Similarity:	154/381 - (40%)	Gaps:	90/381 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPFRRSSLNHRHRDGHVLVWNQRNLHESLEQQPQRCFATRYFV-------TFMLFLGMANAYVMR 58
            ||.:||||             .:.:.|...:.|......:.:.       |.||.||....|..|
  Rat     1 MPSQRSSL-------------MQPIPEETRKTPSAAAEDKRWSRPECQLWTGMLLLGTCLLYCTR 52

  Fly    59 TNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDGEFAWSSALQGYILSSFFYGYVITQ 123
            ..|.|..|||                           |||  |.|:....|.:|||||:||.:||
  Rat    53 VTMPVCTVAM---------------------------SQD--FGWNKKEAGIVLSSFFWGYCLTQ 88

  Fly   124 IPFGILAKKYGSLRFLGYGMLINSVFAFL---VPVAAR-GGGVWGLCAV-RFIQGLGEGPIVPCT 183
            :..|.|..:.|..:.:   :|..|.:.|:   .|:.|. |.|....... |.:.||.:|...|..
  Rat    89 VVGGHLGDRIGGEKVI---LLSASAWGFITVTTPLLAHLGSGHLAFVTFSRILTGLLQGVYFPAL 150

  Fly   184 HAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAF 248
            .::|::.:..:|||...:.|.||:|.||:::..:..:|.:   ..||.|:||..|.:..:|
  Rat   151 TSLLSQRVQESERSFTYSTVGAGSQVGTLVTGGIGSVLLD---RCGWQSVFYFSGGLTLLW---- 208

  Fly   249 LIFVHEDPSSHPTIDEREKKYINDS----------LWGTDVVKSPPIPFKAIIKSLPFYAILFAH 303
            :.:|:              ||:.|.          ..|..|.:...:|::.:.:....:|::.:.
  Rat   209 VYYVY--------------KYLLDEKDLVLALGVLAQGLPVTRPSKVPWRQLFRKASVWAVICSQ 259

  Fly   304 MGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMIS 359
            :.....:..|::.|||:.|:.  |......:.:.:|:|.....|:|...::|.:||
  Rat   260 LSSACSFFILLSWLPTFFKET--FPHSKGWVFNVVPWLLAIPASLFSGFISDRLIS 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	81/341 (24%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	66/275 (24%)
Slc17a9	XP_038961483.1	MFS	38..>326	CDD:421695	81/331 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53923
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820