DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Picot and MFS17

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001015096.2	Gene:	MFS17 / 3354861	FlyBaseID:	FBgn0058263	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	144/532 - (27%)
Similarity:	250/532 - (46%)	Gaps:	76/532 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RDGHVLVWNQRNLHESLEQQPQRCFATRYFVTFMLFLGMANAYVMRTNMSVAIVAMV-------N 70
            |||       |....||.:..   ...|..:.|:.:.|...:::||.:|:.|:|||:       |
  Fly    19 RDG-------RETQSSLLRDK---IPARLVLYFLSWSGFLVSFMMRNDMNFALVAMIANDNSTQN 73

  Fly    71 HTAIKSGE--AEEYDDECGDRDIPIDDSQDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKY 133
            .:.|||.:  ....||:                  .:.::..::|||::.||::|:..|:..:.:
  Fly    74 QSLIKSQQILGTGTDDQ------------------KTIVKSVVISSFYWCYVLSQVVGGVATELF 120

  Fly   134 GSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSR 198
            |:....|:..|..::.:|::|.||:...: .:..:|.|||...|...|..:|::..|||..||||
  Fly   121 GTKCVFGWSQLATALCSFMMPSAAQLHYI-AVIVLRSIQGFASGLTWPAMYAIVGYWIPLTERSR 184

  Fly   199 MGAAVYAGAQFGTIISMPLSG-LLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTI 262
            ..:: :.|...|..::.||.| :|:|:    |||.|||..|.:|..|.|.:.:.....|..||.|
  Fly   185 FMSS-FQGFSIGIGLTYPLCGFILSEW----GWPYIFYTTGTLGLGWCILWYLLAFNTPREHPRI 244

  Fly   263 DERE--------KKYINDSLWGTDVVKSPPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPT 319
            .:.|        ||.:|.|:    .||   :|:..|.||:|.:||.....|..:.:...:...||
  Fly   245 TKDELNYIELNVKKEVNSSV----KVK---VPWLQIFKSIPAWAIAITTFGRIFVHYIFIVNGPT 302

  Fly   320 YMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMISSKRFSHTATRKLINSIGQYGPGVAL 384
            :|..||:|:.::||.||.:|::..::.|:....:||.::..|....|..||:..::.|..|||.:
  Fly   303 FMGNVLKFNFETNGFLSGVPFICSYISSVLFCYIADKIVFYKVLCLTNVRKVFTALSQIIPGVLI 367

  Fly   385 IAASYTGCDRA-LTLAILTIGVGLNGGIYSGFKINHLDLTPRFAGFLMSITNCSA--NLAGLLAP 446
            ....|  .|.. :.|.:..|.|......|:|...|.:||.|.:......:..|..  ..|..::|
  Fly   368 YCIGY--IDNVYILLTVWFIAVIFITASYAGAMANIIDLAPNYGHSAAVLAFCQTIHMSASFISP 430

  Fly   447 IAAGHLISDPSKPMMGQWQIVFFIAAFVYIICGTFYNIFGSGERQYWD-----NPEDDEQKPALQ 506
            :.||.:::  .:..:.||:.||.::|.:.|:...||.:||:.|.|.|:     |.:.||.|
  Fly   431 LTAGFIVT--QEDSIDQWRRVFEVSAIISILTYLFYQLFGTAEIQTWNKGLPVNDDSDEGK---- 489

  Fly   507 TTVTTSPARLSN 518
             .::|:...|.|
  Fly   490 -VLSTAKDDLDN 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	132/485 (27%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	110/396 (28%)
MFS17	NP_001015096.2	2A0114euk	34..477	CDD:129972	131/477 (27%)
MFS17	NP_001015096.2	MFS	41..467	CDD:119392	125/460 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960