DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Picot and CG6978

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	461	Identity:	280/461 - (60%)
Similarity:	347/461 - (75%)	Gaps:	14/461 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 QPQRCFATRYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDS 96
            |..||..||:||..|||.|||||||||||||||||||||||||...::.....|
  Fly    33 QIPRCRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAISHTKSSTQSKE----------- 86

  Fly    97 QDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGG 161
            :||:|.||..|||||||||||||||||||||::.|.||:..|||:||:|||:.||.:|::||.||
  Fly    87 RDGDFEWSYKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGG 151

  Fly   162 VWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGF 226
            |.|||.|||||||||||||||:|::||:|:||||||..|||||||||||||:|||||||||.|||
  Fly   152 VVGLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGF 216

  Fly   227 DGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSLWGTDVVKSPPIPFKAII 291
            |||||||||:||:..|:|.|.|:..|.|.|:....|.|.|:::|.:::|.....:...|||..|.
  Fly   217 DGGWPSIFYIFGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQPEERSRIPFLGIA 281

  Fly   292 KSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADW 356
            ||.||||||.||.|||||||||||.|||||.:||..::::||::|||||||||:.::...::||.
  Fly   282 KSPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADC 346

  Fly   357 MISSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGLNGGIYSGFKINHLD 421
            :| .:.||.|..|||:||:|||||.||||:..:......||..|..:|:||||.||.||||||||
  Fly   347 LI-RRNFSITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKINHLD 410

  Fly   422 LTPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAFVYIICGTFYNIFG 486
            |:|||||.|:|:|||.|||.||:||:.|||:| || ||.:..|:|||:|||.|:|...:|||:|.
  Fly   411 LSPRFAGLLISVTNCVANLVGLMAPMVAGHVI-DP-KPSVENWRIVFYIAAGVFIFTASFYNVFA 473

  Fly   487 SGERQY 492
            ||::|:
  Fly   474 SGKQQW 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	275/452 (61%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	238/384 (62%)
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	276/453 (61%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	269/441 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450665
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378598at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	11	10.800