DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Picot and Slc17a2

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	XP_038951630.1	Gene:	Slc17a2 / 306950	RGDID:	1308821	Length:	487	Species:	Rattus norvegicus

Alignment Length:	475	Identity:	153/475 - (32%)
Similarity:	242/475 - (50%)	Gaps:	43/475 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDGE---- 100
            ||.:..::..........|.::|:||:||||.|        ::.|       |.:.|.:|.
  Rat    26 RYALALVMHFSNFTMITQRVSLSIAIIAMVNST--------QHQD-------PANASAEGPVMNL 75

  Fly   101 -----------------FAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSV 148
                             :.||:..||.|.||..||.::|.||.|.||..:|:.:.||.|:||:|:
  Rat    76 LSNRSRGIKDFSTRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSL 140

  Fly   149 FAFLVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTII 213
            .....|:|| ..||..:..:|.:||:.:|........:.|||.||.|||::.:...:||.||:.|
  Rat   141 LTLFTPLAA-DFGVILVIVIRTVQGMAQGMSWTGQFTIWAKWAPPLERSKLTSIAGSGAAFGSFI 204

  Fly   214 SMPLSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSLWGTD 278
            .:.:.||:::   ..|||.|||:||.:|.|..:.:...:::||..||.|..:||:||..|:....
  Rat   205 ILCVGGLISQ---ALGWPFIFYIFGSIGCVCCVLWFTMIYDDPMHHPCISVKEKEYITSSVAQQS 266

  Fly   279 VVKSPPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAM 343
            ......||.||:::.||.:||......|.:....::|.||||:..||..:::.:|:|||||::|.
  Rat   267 SSPRRSIPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAA 331

  Fly   344 WLFSMFISVVADWMISSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGLN 408
            ...::....:||:::|....|....|||.:|:|...|.:..:|..:.......|:.:|.:..|.:
  Rat   332 SSCTILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFVTSSYIATIVLLILIPGTS 396

  Fly   409 GGIYSGFKINHLDLTPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAF 473
            ....|||.||.||:.||:|.|||.|:......||:::....|.|||..|:   ..|:.|||::|.
  Rat   397 NLCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLISQDSE---SGWRNVFFLSAA 458

  Fly   474 VYIICGTFYNIFGSGERQYW 493
            |.:....||.|||..|.|.|
  Rat   459 VNMFGLIFYLIFGQAEIQNW 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	152/474 (32%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	132/405 (33%)
Slc17a2	XP_038951630.1	MFS_SLC17	30..471	CDD:340876	146/462 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342617
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740