DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Picot and SPCC757.13

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_587688.1	Gene:	SPCC757.13 / 2539039	PomBaseID:	SPCC757.13	Length:	522	Species:	Schizosaccharomyces pombe

Alignment Length:	497	Identity:	107/497 - (21%)
Similarity:	172/497 - (34%)	Gaps:	155/497 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LEQQPQRCFATRYFVTFMLFLGMANAYVMRTNMS-VAIVAMVNHTAIKSGEAEEYDDECGDRDIP 92
            |...|..|      :|:|:      .|:.:|.:| .|:..|...|.|
pombe    75 LVMMPVMC------ITYMI------QYLDKTALSYAALYGMKTDTHI------------------ 109

  Fly    93 IDDSQDGEFAWSSALQGYILSSFFY-GYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVA 156
                 ||. .:||      :::.|| ||::.|.|..||.:|.....|:...:.:.|....|:...
pombe   110 -----DGH-TYSS------MTTLFYAGYLVAQYPAAILMQKCRLSYFIFCNVFLWSAMVCLMAAC 162

  Fly   157 ARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLS-GL 220
            ..|..:.||   ||:.|:.|..|.|....:.|.|....|:.......||......||...|| ||
pombe   163 RNGPSLLGL---RFLAGIFEASITPAFINITAMWYRREEQPMRTLCWYAFNGIAQIIGSILSYGL 224

  Fly   221 LAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKY----INDSLWGTDVVK 281
            ...:|....|..:|.|.|::...|.:.| :|:..:||....:..|||:.    :.|:..|.:..:
pombe   225 GHIHGKVASWRYVFIVIGLMSLGWGVVF-VFIPSNPSKARFLSSREKRIALERVRDNRTGLENKQ 288

  Fly   282 SPPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSL------KSNGL------ 334
                 ||                 ..:.||..:.      .||:..:|      .:||:
pombe   289 -----FK-----------------WKHAYEAFLD------PQVIMITLFTGVCMITNGIGVFSTL 325

  Fly   335 -------------LSSLPYLAMWLFSMFISVVADWMISSKRFSHTATRKLINSIGQYGPGVALIA 386
                         :.::|..|:.:.:||||.|...:..:.|                     |:.
pombe   326 IIKGLGYNELHSAVLNMPLGAIEVAAMFISGVLCKVFKNGR---------------------LLI 369

  Fly   387 ASYTGCDRALTLAILTIGVGLNGGIYSGFKINHLDLTPRFAG--FLMSITNCSANLAGLLAPIAA 449
            ..:..|   ||||          |....:||...:...|..|  |.|.:...||.|..|::...|
pombe   370 GVFMNC---LTLA----------GCLMIWKIPDSNPYGRLVGVWFTMWVPASSALLLSLISSNVA 421

  Fly   450 GHLISDPSKPMMGQWQIVFFIAAFVYIICGTFYN--IFGSGE 489
            |:     :|      :.|.....||:...|...:  :|.||:
pombe   422 GY-----TK------KTVTSATVFVFYSVGNIVSPQLFKSGQ 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	104/485 (21%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	90/419 (21%)
SPCC757.13	NP_587688.1	MFS	80..477	CDD:119392	105/492 (21%)
SPCC757.13	NP_587688.1	2A0114	83..478	CDD:273326	104/483 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto101631
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
TreeFam	0	0.000	Not matched by this tool.
	5	5.050