Protein Alignment Picot and cima-1

DIOPT Version :9

• Sequence 1: NP_725600.1
• Gene: Picot / 36865
• FlyBaseID: FBgn0024315
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001294208.1
• Gene: cima-1 / 24104589
• WormBaseID: WBGene00018473
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 502
• Identity: 108/502 - (21%)
• Similarity: 217/502 - (43%)
• Gaps: 47/502 - (9%)

  Fly    40 RYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDGEFAWS 104
            |..:..||........:..:|::||::.|.:               |     |: ....|...|.
 Worm    67 RLMLAAMLCCCFITLSISSSNLAVALICMTS---------------C-----PV-HGYGGTLEWQ 110

  Fly   105 SALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAVR 169
            |..:|.:|::...|.:| .|..|:.|.:......:..|:|:..:...::|:.| ....|.....|
 Worm   111 SQQEGLVLAAQNAGSLI-MIVTGMWADRLNGKWMVFIGLLLCCIGNLMLPLLA-SKSFWFAVLAR 173

  Fly   170 FIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSG-LLAEYGFDGGWPSI 233
            ...|..:..::|..::::.:|.|..||......:..|.|.||:..:|.:| |........|||:|
 Worm   174 ISIGASDACLMPAVNSLITRWFPQAERPAAIGLISGGRQIGTLFILPTAGYLCTRKDILDGWPAI 238

  Fly   234 FYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYIN-----DSLWGTDVVKSPPIPFKAIIKS 293
            ||:...:..:.::.::.|..:.|:....|..|||::|.     :|: |....::..:|:.|::.|
 Worm   239 FYLSATISVLVTVFWIPFGADKPAKQICISSREKEFIETRIACESI-GKRTDRTRRVPYGAMLHS 302

  Fly   294 LPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMI 358
            .|.:|.:||.:.|.|....::..||.||:.||.|:...||::::||.|.::|...|.|.::.::.
 Worm   303 KPLWACIFALICHEYPLVIMLQFLPNYMRDVLEFAPTKNGIIAALPILCLFLSKTFSSSLSSYLT 367

  Fly   359 SSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGLNGGIYS-GFKINHLDL 422
            :..|...|...|..|::...|..:.:....:...:.|........|..:..|::: |.....:.:
 Worm   368 TKLRLDKTFVCKGFNAVASAGLAICISFVPFFNKESAFLAVFCLCGAMIFAGLHTPGVITAMVQI 432

  Fly   423 TPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAFVYIICGTFYNIFGS 487
            .|.|:|.:...:..:.....:...|...:::...|   :.:|.:||.::|.|..:....:.|:||
 Worm   433 APAFSGIITGWSFFAVAWFSIGNKILTKYIVQSGS---VTEWGMVFRVSALVAALPVIVFTIWGS 494

  Fly   488 GERQYWDNPED-------------DEQKPALQTTVTTSPARLSNGST 521
            .:|::|..|..             |..:...:.|.:||..:.|..|:
 Worm   495 ADREWWAAPSSKCSVASFHRPSIRDRSREMSRATSSTSLGQQSRVSS 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	102/479 (21%)
		MFS	100..485	CDD:119392	86/391 (22%)
cima-1	NP_001294208.1	2A0114euk	63..506	CDD:129972	102/465 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910