Protein Alignment Picot and cima-1

DIOPT Version :10

• Sequence 1: NP_725600.1
• Gene: Picot / 36865
• FlyBaseID: FBgn0024315
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001294208.1
• Gene: cima-1 / 24104589
• WormBaseID: WBGene00018473
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 502
• Identity: 108/502 - (21%)
• Similarity: 217/502 - (43%)
• Gaps: 47/502 - (9%)

  Fly    40 RYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDGEFAWS 104
            |..:..||........:..:|::||::.|.:               |     |: ....|...|.
 Worm    67 RLMLAAMLCCCFITLSISSSNLAVALICMTS---------------C-----PV-HGYGGTLEWQ 110

  Fly   105 SALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAVR 169
            |..:|.:|::...|.:| .|..|:.|.:......:..|:|:..:...::|:.| ....|.....|
 Worm   111 SQQEGLVLAAQNAGSLI-MIVTGMWADRLNGKWMVFIGLLLCCIGNLMLPLLA-SKSFWFAVLAR 173

  Fly   170 FIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSG-LLAEYGFDGGWPSI 233
            ...|..:..::|..::::.:|.|..||......:..|.|.||:..:|.:| |........|||:|
 Worm   174 ISIGASDACLMPAVNSLITRWFPQAERPAAIGLISGGRQIGTLFILPTAGYLCTRKDILDGWPAI 238

  Fly   234 FYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYIN-----DSLWGTDVVKSPPIPFKAIIKS 293
            ||:...:..:.::.::.|..:.|:....|..|||::|.     :|: |....::..:|:.|::.|
 Worm   239 FYLSATISVLVTVFWIPFGADKPAKQICISSREKEFIETRIACESI-GKRTDRTRRVPYGAMLHS 302

  Fly   294 LPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMI 358
            .|.:|.:||.:.|.|....::..||.||:.||.|:...||::::||.|.::|...|.|.::.::.
 Worm   303 KPLWACIFALICHEYPLVIMLQFLPNYMRDVLEFAPTKNGIIAALPILCLFLSKTFSSSLSSYLT 367

  Fly   359 SSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGLNGGIYS-GFKINHLDL 422
            :..|...|...|..|::...|..:.:....:...:.|........|..:..|::: |.....:.:
 Worm   368 TKLRLDKTFVCKGFNAVASAGLAICISFVPFFNKESAFLAVFCLCGAMIFAGLHTPGVITAMVQI 432

  Fly   423 TPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAFVYIICGTFYNIFGS 487
            .|.|:|.:...:..:.....:...|...:::...|   :.:|.:||.::|.|..:....:.|:||
 Worm   433 APAFSGIITGWSFFAVAWFSIGNKILTKYIVQSGS---VTEWGMVFRVSALVAALPVIVFTIWGS 494

  Fly   488 GERQYWDNPED-------------DEQKPALQTTVTTSPARLSNGST 521
            .:|::|..|..             |..:...:.|.:||..:.|..|:
 Worm   495 ADREWWAAPSSKCSVASFHRPSIRDRSREMSRATSSTSLGQQSRVSS 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	102/479 (21%)
cima-1	NP_001294208.1	2A0114euk	63..506	CDD:129972	102/465 (22%)