Protein Alignment Picot and SLC37A2

DIOPT Version :10

• Sequence 1: NP_725600.1
• Gene: Picot / 36865
• FlyBaseID: FBgn0024315
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_938018.1
• Gene: SLC37A2 / 219855
• HGNCID: 20644
• Length: 505
• Species: Homo sapiens
• Alignment Length: 521
• Identity: 112/521 - (21%)
• Similarity: 186/521 - (35%)
• Gaps: 138/521 - (26%)

  Fly    40 RYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQD-GEFAW 103
            |..:..:.||..|..::.|..:|:          :||    .....|.::..||:|:.. .:..|
Human    22 RGLILLLTFLIYACYHMSRKPISI----------VKS----RLHQNCSEQIKPINDTHSLNDTMW 72

  Fly   104 SS----------ALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAAR 158
            .|          .|.|.:.::|...|.|.....|:..::.....:|..|||::.:|..|.
Human    73 CSWAPFDKDNYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLF----- 132

  Fly   159 GGG-------VWGLCAVRFIQGL----GEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTI 212
            |.|       :|....::...||    |...:|.|    :..|....:|..:.....:....|.|
Human   133 GLGYFWNIHELWYFVVIQVCNGLVQTTGWPSVVTC----VGNWFGKGKRGFIMGIWNSHTSVGNI 193

  Fly   213 ISMPLSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFV--------------H---------- 253
                |..|:|....:|.|...|.|.||:..|..:...:|:              |
Human   194 ----LGSLIAGIWVNGQWGLSFIVPGIITAVMGVITFLFLIEHPEDVDCAPPQHHGEPAENQDNP 254

  Fly   254 EDPSSHPTIDEREKKYINDSLWGTDVV----KSP-----PIPFKAIIKSLP-----FYAILFAHM 304
            |||.:.|.       .|.:|  |.:.|    |.|     .|.|...:: :|     ...:|||.:
Human   255 EDPGNSPC-------SIRES--GLETVAKCSKGPCEEPAAISFFGALR-IPGVVEFSLCLLFAKL 309

  Fly   305 GHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADW------------- 356
               ..| |.:..||.|:..|..||.|..|.||:|..:...:..:...:|:|:
Human   310 ---VSY-TFLYWLPLYIANVAHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRATTCCVMLI 370

  Fly   357 MISSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGLNGGIYSGFKINHLD 421
            :.:...|       |.|.|||.|...:::.....|.......|::|..|..:.|.:...|.|...
Human   371 LAAPMMF-------LYNYIGQDGIASSIVMLIICGGLVNGPYALITTAVSADLGTHKSLKGNAKA 428

  Fly   422 LTPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFF--IAAFV---YIICGTF 481
            |:.     :.:|.:.:.::...|.|:.|| |||...      |..||:  |:|.|   .::|...
Human   429 LST-----VTAIIDGTGSIGAALGPLLAG-LISPTG------WNNVFYMLISADVLACLLLCRLV 481

  Fly   482 Y 482
            |
Human   482 Y 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	111/520 (21%)
SLC37A2	NP_938018.1	MFS_SLC37A1_2	22..484	CDD:340902	112/521 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..262		4/21 (19%)