DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Picot and H11E01.2

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_508300.3	Gene:	H11E01.2 / 186721	WormBaseID:	WBGene00019187	Length:	470	Species:	Caenorhabditis elegans

Alignment Length:	500	Identity:	105/500 - (21%)
Similarity:	190/500 - (38%)	Gaps:	97/500 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDG--EFA 102
            ||.|   |.:|......:.:||:|     :|.|.|...:..|.        :|..| |:|  .|:
Worm    18 RYIV---LAIGTLCIASIASNMTV-----INFTMICMAKPSEL--------VPTTD-QEGTINFS 65

  Fly   103 WSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCA 167
            :|:..:..|:.:...|.:....||....:|:|:.|........:::...|:|:||.....: |..
Worm    66 YSNEQKSVIMWAAAVGTLAAAWPFHWFYEKFGARRVFFAAGAFSTISTALMPLAAHIHFNF-LVV 129

  Fly   168 VRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDGGWPS 232
            .||.||:..|........::..|....:.....:.:.:.:|...:.:||::|.|.|..:  ||.|
Worm   130 ARFFQGVSFGADFAAIGLIVVNWASLKQHGLFISLLSSFSQISVMFTMPVAGELCESKY--GWES 192

  Fly   233 IFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSLWGTDVVKS-PPIPFKAIIKSLPF 296
            ::|....|.....:.:..|..::||.||.:.|.|.:.|..   |...||. ...|...|:.:...
Worm   193 VYYGHAAVSGALFVLWAWFYRDNPSKHPQMTETELEKIRR---GKGEVKEHEKAPIAKILTNPVM 254

  Fly   297 YAILFAHMGHNYGYETLMTEL-----PTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVAD- 355
            .::..:..|     |.:|::.     ||::|:||.|::...|...::|......|.:...:.:|
Worm   255 QSVWLSAFG-----ELMMSQFIVMYEPTFLKEVLGFTVNHTGYFVAIPRALHLTFKIISGIASDR 314

  Fly   356 ---WMISSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRA----LTLAILTIGVG-LNGGIY 412
               |...||       .::.|:|...|.|.......|...:.|    :.|.|:....| :.||.|
Worm   315 ISFWTEKSK-------MRIFNTIALMGSGTFFCVLGYIPKEHAHLSLVALIIIECSTGFICGGFY 372

  Fly   413 ----------SGFKINHLDLTPRFAGF---LMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQW 464
                      |.|.::.:......:.|   |:....|::|                    .:.:|
Worm   373 KCATLVARQHSHFVLSQIQFIKCLSLFIEPLLVFLICTSN--------------------TLEEW 417

  Fly   465 QIVFFIAAFVYIICGTFYNIFGSGERQYWDNPED------DEQKP 503
            :|||.....:.|.....:..|.:      |.|.|      :|:.|
Worm   418 RIVFLTHGILLIAGNIIFCYFAT------DRPADFTHTLVEEELP 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	102/495 (21%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	83/412 (20%)
H11E01.2	NP_508300.3	MFS	19..439	CDD:391944	98/474 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160198
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740