Protein Alignment Picot and eat-4

DIOPT Version :10

• Sequence 1: NP_725600.1
• Gene: Picot / 36865
• FlyBaseID: FBgn0024315
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_499023.3
• Gene: eat-4 / 176291
• WormBaseID: WBGene00001135
• Length: 576
• Species: Caenorhabditis elegans
• Alignment Length: 506
• Identity: 152/506 - (30%)
• Similarity: 248/506 - (49%)
• Gaps: 47/506 - (9%)

  Fly    40 RYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDGEFAWS 104
            |:.:..:..:|...::.:|.|...|          |:...:.|.|       |.......||.|:
 Worm    69 RWLLAILANMGFMISFGIRCNFGAA----------KTHMYKNYTD-------PYGKVHMHEFNWT 116

  Fly   105 SALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAVR 169
            ......:.||:||||::||||.|.||.|:...:..|:|:.:.:....|:|...:....:.:..::
 Worm   117 IDELSVMESSYFYGYLVTQIPAGFLAAKFPPNKLFGFGIGVGAFLNILLPYGFKVKSDYLVAFIQ 181

  Fly   170 FIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDGGWPSIF 234
            ..|||.:|...|..|.:...|.||.|||::....:.|:..|.::.:|||..|..|   ..|.:.|
 Worm   182 ITQGLVQGVCYPAMHGVWRYWAPPMERSKLATTAFTGSYAGAVLGLPLSAFLVSY---VSWAAPF 243

  Fly   235 YVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSLWGTDVVKSPP----IPFKAIIKSLP 295
            |::|:.|.:|:|.:.....|.|:.||||.:.||.:|.|::  ..|..:.|    ||:|||:.|.|
 Worm   244 YLYGVCGVIWAILWFCVTFEKPAFHPTISQEEKIFIEDAI--GHVSNTHPTIRSIPWKAIVTSKP 306

  Fly   296 FYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMISS 360
            .:||:.|:...::.:..|:....||||:.|...:..:|||:::|:|.|....:....:||::.|:
 Worm   307 VWAIIVANFARSWTFYLLLQNQLTYMKEALGMKIADSGLLAAIPHLVMGCVVLMGGQLADYLRSN 371

  Fly   361 KRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGLNGGIYSGFKINHLDLTPR 425
            |..|.||.||:.|..|..|....::..:||..|....:|::. .||::|...|||.:||||:.||
 Worm   372 KILSTTAVRKIFNCGGFGGEAAFMLIVAYTTSDTTAIMALIA-AVGMSGFAISGFNVNHLDIAPR 435

  Fly   426 FAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAFVYIICGTFYNIFGSGER 490
            :|..||..:|....||||..|... ...:..||   ..|..||.:|:.::....|||.::.|||.
 Worm   436 YAAILMGFSNGIGTLAGLTCPFVT-EAFTAHSK---HGWTSVFLLASLIHFTGVTFYAVYASGEL 496

  Fly   491 QYWDNPEDDEQ----------------KPALQTTVTTSPARLSNGSTAPAA 525
            |.|..|:::|:                ..|.:||.|..||.:.:...|.||
 Worm   497 QEWAEPKEEEEWSNKELVNKTGINGTGYGAAETTFTQLPAGVDSSYQAQAA 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	141/463 (30%)
eat-4	NP_499023.3	MFS_SLC17A6_7_8_VGluT	73..492	CDD:340940	135/445 (30%)