DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Picot and Slc17a1

DIOPT Version :9

Sequence 1:	NP_725600.1	Gene:	Picot / 36865	FlyBaseID:	FBgn0024315	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_598238.2	Gene:	Slc17a1 / 171080	RGDID:	620099	Length:	465	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	150/473 - (31%)
Similarity:	242/473 - (51%)	Gaps:	34/473 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RCFATRY--FVTF----MLFLGMANAYVM--RTNMSVAIVAMVN-----HTAIKSGEAEEYDDEC 86
            ||...:.  |.:|    .:.|...|..:|  |..:::.:|||||     |.:.|| .||
  Rat     4 RCLPKKVPGFCSFRYGLAILLHFCNIVIMAQRVCLNLTMVAMVNKTEPPHLSNKS-VAE------ 61

  Fly    87 GDRDIPIDDSQDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAF 151
                 .:|:.::...:||..:||.||||.|.|.|:.|:|.|.|:..|...:.:|..:.::||.:.
  Rat    62 -----MLDNVKNPVHSWSLDIQGLILSSVFLGMVVIQVPVGYLSGAYPMKKIIGSSLFLSSVLSL 121

  Fly   152 LVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMP 216
            |:|.||:.|... :...|.:||:.:|.:....|.:..||.||.||.|:.:...:|...|..|::.
  Rat   122 LIPPAAQVGAAL-VIVCRVLQGIAQGAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALL 185

  Fly   217 LSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSLWGTDVVK 281
            :||.:.:.   .|||.:||:|||||.|.|:.:.|...:||::||.:...||.||..||.......
  Rat   186 VSGFICDL---LGWPMVFYIFGIVGCVLSLFWFILFFDDPNNHPYMSSSEKDYITSSLMQQVHSG 247

  Fly   282 SPPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLF 346
            ...:|.||::||||.:||:.......:....|:|..||::...|..:::.||||||||||..::.
  Rat   248 RQSLPIKAMLKSLPLWAIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYIC 312

  Fly   347 SMFISVVADWMISSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGLNGGI 411
            .:....::|:::|.|.||..|.|||..::|.:.|.:.::...|...:...|:..||:........
  Rat   313 GIVAGQMSDFLLSRKIFSVVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYSTVIFLTLANSTLSFS 377

  Fly   412 YSGFKINHLDLTPRFAGFLMSITNCSANLAGLLAPIAAGHLIS-DPSKPMMGQWQIVFFIAAFVY 475
            :.|..||.||:.||:.|||.::|.......||::...||.::: ||..    .|...||:.|.:.
  Rat   378 FCGQLINALDIAPRYYGFLKAVTALIGIFGGLISSTLAGLILNQDPEY----AWHKNFFLMAGIN 438

  Fly   476 IICGTFYNIFGSGERQYW 493
            :.|..||.:|..|:.|.|
  Rat   439 VTCLAFYLLFAKGDIQDW 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	148/467 (32%)
Picot	NP_725600.1	MFS	100..485	CDD:119392	127/385 (33%)
Slc17a1	NP_598238.2	2A0114euk	1..464	CDD:129972	150/473 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910