Protein Alignment Picot and SLC17A3

DIOPT Version :10

• Sequence 1: NP_725600.1
• Gene: Picot / 36865
• FlyBaseID: FBgn0024315
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 143/473 - (30%)
• Similarity: 237/473 - (50%)
• Gaps: 27/473 - (5%)

  Fly    33 PQRCFATRYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDD-- 95
            |..|.| ||.:..:|.............|::.:|||||.|:.:|    :.:|  ....:|:|.
Human    32 PSLCSA-RYGIALVLHFCNFTTIAQNVIMNITMVAMVNSTSPQS----QLND--SSEVLPVDSFG 89

  Fly    96 ----------SQDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFA 150
                      ::...:.||..:||.|..:..||.::|..|.|.||.:.|:.|.:|..:...|...
Human    90 GLSKAPKSLPAKAPVYDWSPQIQGIIFGAVGYGGILTMAPSGYLAGRVGTKRVVGISLFATSFLT 154

  Fly   151 FLVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISM 215
            ..:|:|...|.|. |...|.:|||.:..|:....|:..||.||.||||:.:...:|...|...::
Human   155 LCIPLATDFGIVL-LIVTRIVQGLSQSSILGGQFAIWEKWGPPQERSRLCSIALSGMLLGCFTAI 218

  Fly   216 PLSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSLWGTDVV 280
            .:.|.::|   ..|||.:||:||.||.|..:.:.:.:::||.|:|.|...||:||..||......
Human   219 LIGGFISE---TLGWPFVFYIFGGVGCVCCLLWFVVIYDDPVSYPWISTSEKEYIISSLKQQVGS 280

  Fly   281 KSPPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWL 345
            ...|:|.||:::|||.::|......|.:...|::..:|||:..|...:::.|||||:||::..|:
Human   281 SKQPLPIKAMLRSLPIWSICLGCFSHQWLVSTMVVYIPTYISSVYHVNIRDNGLLSALPFIVAWV 345

  Fly   346 FSMFISVVADWMISSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGLNGG 410
            ..|....:||::: :|:|.....||:...:|.......:::..|.........|:||:..||:..
Human   346 IGMVGGYLADFLL-TKKFRLITVRKIATILGSLPSSALIVSLPYLNSGYITATALLTLSCGLSTL 409

  Fly   411 IYSGFKINHLDLTPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAFVY 475
            ..||..||.||:.||::.|||..:...:::|.::.|..:|.|:|  ..|..| |:.|||:...|.
Human   410 CQSGIYINVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFLLS--QDPEFG-WRNVFFLLFAVN 471

  Fly   476 IICGTFYNIFGSGERQYW 493
            ::...||.|||..:.|.|
Human   472 LLGLLFYLIFGEADVQEW 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Picot	NP_725600.1	2A0114euk	41..501	CDD:129972	139/465 (30%)
SLC17A3	NP_001091956.1	MFS_SLC17	42..482	CDD:340876	134/453 (30%)