Protein Alignment Nach and scnn1b

DIOPT Version :9

• Sequence 1: NP_001334724.1
• Gene: Nach / 36864
• FlyBaseID: FBgn0024319
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 640
• Identity: 123/640 - (19%)
• Similarity: 238/640 - (37%)
• Gaps: 186/640 - (29%)

  Fly    21 GYLRR---TWSDFCATSSIHGLKYTRDEDTNKIVHLVWLLISVV----MFICAVVMARTFYMDYR 78
            ||..:   .|  ||..::.||.|....|...|  .::|.::::|    :|....|:..| |:.|.
 Frog    25 GYTYKELLVW--FCDNTNTHGPKRIIKEGPKK--RVMWFILTLVFAGLVFWQWGVLILT-YLSYG 84

  Fly    79 SSPTRMNVESDNTPVNRLYFPPVTICPDVLFNMQKSEAFLNTLRLPKGAELRGILRKLHIFYGFM 143
            .|      .|.:.....:.||.||:|        .:..:       |.:.::.:|:.|.......
 Frog    85 VS------VSLSIGFKTMEFPAVTVC--------NANPY-------KYSRVKPLLKDLDALVATA 128

  Fly   144 LDDERYSAEDIEQMEALLFL-----NNLTIPEFVEHLRWN------CDEILYRCRFNGEIMDCSK 197
            ||..::|::|    :|..|.     .|:|:    :...||      .||..........|.|.:.
 Frog   129 LDRIQFSSQD----QANTFTQSSTNQNVTL----DPTLWNHIPLVVIDETDPSNPIVNNIFDNNA 185

  Fly   198 IFQLSKTF-------FGHCCSFNLRQKGWVNNK-----------LNNLESFKVFHLNS------- 237
            |:..:.:|       ..:...:.:..|...||.           :..|:.:.:..|:|
 Frog   186 IYSKNNSFRNSSEDQTSYSQRYKVAMKLCTNNNTQCVYRNFTSGIQALQEWYLLQLSSIFSNVPL 250

  Fly   238 -----LNFTAQRAI-----GG-------------LRYGLSVVVRYKDDNYDPLQSYS----YGVK 275
                 :.|.|:..|     ||             ..||...:..:..:..||:.|.:    :|:|
 Frog   251 ADRIAMGFKAEDLILTCLFGGQPCSYRNFTRIYDADYGNCYIFNWGQEGEDPMASANPGADFGLK 315

  Fly   276 LL--IQEADAFP--SAHSAAKFIAFNSETFAAVRPQETFCSSAVK---ALIIEE--------RNC 325
            |:  |::.:..|  ...:||:.|.....:|..|:....:.....:   |:::::        .:|
 Frog   316 LVLDIEQGEYLPYVQTTAAARLILHQQRSFPFVKDLGIYAMPGTETSIAVLVDQLEHMEAPYSSC 380

  Fly   326 -VFQNEFPMR-----YFSDYVYPNCELNCRVTNMVKFCGCHTYFFDFNRTSDRICT---FRD-IP 380
             |..::.|::     :.|.|...:|..:|....||:.|||..|.:.....|: .|:   :.| :|
 Frog   381 TVNGSDIPVQNLYAEFNSSYSIQSCLRSCYQEQMVQTCGCADYQYPLPNGSE-YCSNDKYPDWVP 444

  Fly   381 C---LVDNFGRLLLICSKYSDFNRLLSANIITRKKSTQCYCPLTCEHIDYD--VQLTNFP----- 435
            |   |.|:                      :..::|....|...|....|.  :.:.::|
 Frog   445 CYYGLRDS----------------------VADRESCISLCQQPCNDTQYKMVISMADWPSAGAQ 487

  Fly   436 ---LELNMPVADKFYSGLAKNDGV--LHVFINSFSYRRLRRDLLSNMVTLVSNLGSAFSLFVGMS 495
               ..:.....|..::.....:|:  |:::...|:||.:.....:|:|.|:||||..|..::|.|
 Frog   488 DWIFHVLSYEKDSSHNITVNRNGIVRLNIYFQEFNYRSITESEATNVVWLLSNLGGQFGFWMGGS 552

  Fly   496 MLSVVEIIYYFSVILRKNYKLECE--TRSQMLHKKPKFAWPKANDTHSKEQKSVF 548
            :|.::|    |..|:     ::|.  |..::|      ||.|  |...:.|::.:
 Frog   553 VLCIIE----FGEII-----IDCVWITILKLL------AWIK--DRRQRRQRAQY 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	None
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	121/638 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48391
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920