DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nach and ppk19

DIOPT Version :9

Sequence 1:	NP_001334724.1	Gene:	Nach / 36864	FlyBaseID:	FBgn0024319	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_651708.2	Gene:	ppk19 / 43489	FlyBaseID:	FBgn0039679	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	526	Identity:	119/526 - (22%)
Similarity:	209/526 - (39%)	Gaps:	115/526 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ATSSIHGLKYTRDEDTNKIVHL----VWLLISVVMFICAVVMARTFY--MDYRSSPTRM--NVES 88
            |.|:|||:::...|.     ||    :||.|    .:.||:...:.|  :.:|.|...:  .:|:
  Fly    38 AHSNIHGMQHVFGEQ-----HLWQRCLWLAI----VLGAVITGFSLYTVLMHRHSEQLLVSLIET 93

  Fly    89 DNTPVNRLYFPPVTICPDVLFNMQKS-EAFLNTLRLPKGAELRGILRKLHIFYGFMLDDERYSAE 152
            ...||..:.||.|.:||...||.|:: .||:..|.....||||...|:|
  Fly    94 TQLPVYHIDFPAVAVCPWNHFNWQRAPSAFIRFLPRHPNAELRETFRQL---------------- 142

  Fly   153 DIEQMEALLFLN----------NLT------IPEFVEHLRWNCDEILY--RCRFNGEIMDCSKIF 199
             :..|:.:.|.|          |||      :.:.:..:.:.|||:..  .|.|:....||.|:|
  Fly   143 -LASMDIMNFSNFNRIRILTKRNLTGISYLKMTDLMNFMTYRCDELFVADSCVFDETPYDCCKLF 206

  Fly   200 QLSKTFFGHCCSF------NLRQKGWVNNKLNNLESFKVFHLNSLNFTAQRAIGGLRYGLSVVVR 258
            ...:|..|.|..|      |.|:|..:|.          |:.:.|:...:.:  ||::.::....
  Fly   207 VREQTVKGQCLVFNSMISENSRKKHLINQ----------FYPHKLSTAGEDS--GLKFTINASYS 259

  Fly   259 YKDDNYDPLQSYSYGVKLLIQEADAFPSAHSAAKFIAFNSETFAAVRPQETFCSSAVKALIIEER 323
            :. :|.|.|.  .:|:.|:|:|...:  ::.....:..::|.|.||.|..|..|.....:..::|
  Fly   260 FM-NNIDALT--PFGMNLMIKEPRQW--SNEMMYHLYPDTENFVAVHPLVTETSPNTYEMSPKKR 319

  Fly   324 NCVFQNEFPMRYFSDYVYPNCEL-----NCRVT--NMVKFCGCHTYFFDFNRTSDRI--CTFRDI 379
            .|.|.:|      .:..:.|..|     ||.|.  ::|.:..|......|....|.:  |...|.
  Fly   320 RCYFDDE------KNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPECGINDA 378

  Fly   380 PCLVDNFGRLLLICSKYSDFNRLLSANIITRKKSTQCYCPLTCEHIDYDVQLTNFPLELNMPVAD 444
            .||.:|......:  |..|..:.::.:    ::...|.||..|....|::.|....|:......|
  Fly   379 QCLGNNSDIFTYV--KMGDQEKYINDS----RQGHFCDCPDNCNSRLYEMSLNVRKLDYPKNSTD 437

  Fly   445 KF-----YSGLAKNDGVLHVFINSFSYRRLRRDLLSNMVTLVSNLGSAFSLFVGMSMLSVVEIIY 504
            :.     |.|    ..|:...|....|..         :.|::|.|...||::|.|::|.:|:::
  Fly   438 QLIKAQVYYG----QRVMTKIITKLKYTN---------IDLLANFGGIISLYIGASVMSFIELLF 489

  Fly   505 YFSVIL 510
            ....::
  Fly   490 VLGKLM 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	None
ppk19	NP_651708.2	ASC	39..489	CDD:279230	118/517 (23%)
ppk19	NP_651708.2	AceK	116..>139	CDD:295079	8/22 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I4697
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020