DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nach and ppk30

DIOPT Version :9

Sequence 1:	NP_001334724.1	Gene:	Nach / 36864	FlyBaseID:	FBgn0024319	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_001263076.1	Gene:	ppk30 / 43487	FlyBaseID:	FBgn0039677	Length:	457	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	96/492 - (19%)
Similarity:	172/492 - (34%)	Gaps:	142/492 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 MFICAVVMARTFYMDYRSSPTRMNVESDNTPVNRLYFPPVTICPDVLFNMQKSEAFLNTLRL--- 123
            :::..:...|.||...::|     :|..:..|:.:.||.|||.| :..::.|:|.......|
  Fly    54 VYVSILSSERYFYYWVQTS-----IERTDMHVSEIDFPAVTIIP-INLSILKAEKLSKAYNLVQS 112

  Fly   124 -----PKGAELRGILRKLHIFYGFMLDDERYSA-EDIEQMEALLFLNNLTIPEFVEHLRWNCDEI 182
                 |..|.               |.||.::. .::|...|..:       ...:.|:.||...
  Fly   113 VVWQTPMSAR---------------LTDENFTEFSELENWNAQSW-------GIYQALQMNCQHF 155

  Fly   183 LYRCRFNGEIMDCSKIFQLSKTFFGHCCSFNL-----RQKGW------------VNNKLNNLESF 230
            ...|::..:.|:|..:|:.:|||.|....||.     |.:.|            :|.|:...:.
  Fly   156 FTECQWRRKAMNCCDLFRPTKTFNGFAFEFNSLVSSGRDETWPWSVASCGSYSGLNVKIKRQQG- 219

  Fly   231 KVFHLNSLNFTAQRAIGGLRYGLSVVVRYKDDNYDPLQSYSYGVKLLIQEADAFPSAHSAAKFIA 295
             ::.||:               :.|:|      ::|.|.....:....::....|     .:.:.
  Fly   220 -LYTLNT---------------MGVIV------HEPTQLLGMSIDYSSEDRIVVP-----VEPLH 257

  Fly   296 FNSETFAAVRPQETFCSSAVKALIIEERNCVFQNEFPM-RYFSDYVYPNCELNCRVTNMVKFCGC 359
            |.:|.....||             ::.|.|.|:||.|. :..|:.:|     .|.|..::..|.|
  Fly   258 FTAELDVRARP-------------VQMRRCYFENEIPTGKSRSECIY-----KCHVNYIISKCNC 304

  Fly   360 HTYFFDFNRTSD-------------RICTFRDIPCLVDNFGRLLLICSKYSDFNRLLSANIITRK 411
             :.......|.|             |||..:|:.|.  |..||.|..          .:|||...
  Fly   305 -SLELPVKATQDEDNIAAAKESNGRRICGVKDLACF--NQHRLSLFS----------MSNIIEES 356

  Fly   412 K-----STQCYCPLTCEHIDYDVQLTNFPLELNMPVADKFYSGLAKNDGVLHVFINSFSYRRLRR 471
            :     :..|.|...|.|..|........:..:..:|......:...:..|      ||||.:.|
  Fly   357 RDNVFSTVDCGCFPQCGHTQYHTSTYTEKMSAHTNLAAAIEIDVYFQEETL------FSYRSMLR 415

  Fly   472 DLLSNMVTLVSNLGSAFSLFVGMSMLSVV-EIIYYFS 507
               ..::.|:.:.|....|.:|:|:|..: |::..|:
  Fly   416 ---FTLIDLMVSYGGIAGLIMGISVLGCINELLDRFA 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	None
ppk30	NP_001263076.1	ASC	47..446	CDD:279230	95/487 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26184
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.030