DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nach and egas-4

DIOPT Version :9

Sequence 1:	NP_001334724.1	Gene:	Nach / 36864	FlyBaseID:	FBgn0024319	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_501207.2	Gene:	egas-4 / 3564809	WormBaseID:	WBGene00018906	Length:	883	Species:	Caenorhabditis elegans

Alignment Length:	369	Identity:	78/369 - (21%)
Similarity:	134/369 - (36%)	Gaps:	89/369 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 LRWNCDEILYRCRFNGEIMDCSKIF-QLSKTFFGHCCSFNLRQKGWVNNKLNNLESFKVFHLNSL 238
            |.|...::.....:..:::|.:..| |.:....|:|.:||                    |:||
Worm   577 LSWTAADMFLWVAYEQQLIDLNSNFVQWNDKVLGNCFTFN--------------------HMNS- 620

  Fly   239 NFTAQRAIGGLRYGLSVVVRYKDDNYDPLQSYSYGVKLLI---QEADAFPSA--HSAAKF---IA 295
            :|..:....|...||.:.:..|.|.|.| .:.:.||.:..   :||....|.  ::|..|   ||
Worm   621 SFKYEARSSGYPGGLEMQMNVKQDEYLP-WTETAGVMVFTSTKEEAVTSESVRINTAPHFESRIA 684

  Fly   296 FNSETFAAVRPQETFCSSAVKALIIEERNCVFQNEFPMRYF-SDYVYPNCELNCRVTNMVKFCGC 359
            .|...:..:..:...|.::|             :|....|: .||....|..:|....:...|||
Worm   685 INRVDYYRLGGRYGVCINSV-------------SEVKSYYYDGDYTTDGCLRSCYQDVVNGDCGC 736

  Fly   360 HTYFFD--FNRTSDRI-CTFRDIPC---LVDNFGRLLLICSKYSDFNRLLSANIITRKKST--QC 416
                .|  :...:|.| |:.....|   |||:.|                       ..||  :|
Worm   737 ----MDPRYPMPNDGISCSISQKTCIDELVDSRG-----------------------DPSTWPEC 774

  Fly   417 YCPLTCEHIDYDVQLTNFPLELNMPVADKFYSGLAK------NDGVLHVFINSFSYRRLRRDLLS 475
            .|||.|....|..:|:..|....:...::.|:....      :..:|.:.:....|.........
Worm   775 TCPLPCSQTVYTSKLSRLPYVNKIVDCEEAYTNKTACYETFLDSVILRISLPKLDYMIYSETPAM 839

  Fly   476 NMVTLVSNLGSAFSLFVGMSMLSVVEIIYYF---SVILRKNYKL 516
            ::...:|.||...|:.:|:|::|.||:.:.|   .|||..|.:|
Worm   840 DLTKFMSYLGGILSILIGVSIVSFVELFFLFVQLIVILLFNKRL 883

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	None
egas-4	NP_501207.2	EGF	101..131	CDD:278437
		EGF_CA	482..522	CDD:238011
		ASC	<610..869	CDD:279230	67/320 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920