DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nach and ppk

DIOPT Version :9

Sequence 1:	NP_001334724.1	Gene:	Nach / 36864	FlyBaseID:	FBgn0024319	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_477232.1	Gene:	ppk / 34843	FlyBaseID:	FBgn0020258	Length:	606	Species:	Drosophila melanogaster

Alignment Length:	558	Identity:	122/558 - (21%)
Similarity:	223/558 - (39%)	Gaps:	80/558 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DFCATSSIHGLKYTRDEDTNKIVHLVWLLISVVMFICAVVMARTFYMDYRSSPTRMNVESDNTPV 93
            ::..:::|||::|..:........|.||..:.:....||.:....|:.::.||..:..:....||
  Fly    68 EYAKSTTIHGIRYIFEVHRPIYEKLYWLFFTCISVYFAVSLIWDTYLKWQESPVILGFDETLVPV 132

  Fly    94 NRLYFPPVTICPDVLFNMQKSEAFLNTLRLPKGAELRGILRKLHIFY---GFM--LDDERYS--- 150
            :::.||.:||||::  .|::: .|          :...:.|:|...|   |.:  ||||..:
  Fly   133 HKIPFPTITICPEI--KMERN-VF----------DYTNVSRQLWEEYKQNGNISDLDDEDLARMA 184

  Fly   151 -------AEDIEQMEALLF-LN--NLTIPEFVEHLRWNCDEILYRCRFNGEIMDCSKIFQLSKTF 205
                   :|.:::...||. ||  |:.:.:.:..|..:.:|....|::||....|.|||....|.
  Fly   185 VAMHICDSEVVQRFTPLLSQLNPPNVDVTQTLIDLSISKNETGPFCKWNGRFYFCDKIFDFVATD 249

  Fly   206 FGHCCSFN-LRQKG----------------------------WVNNKLNNLESFKVFHLNSLNFT 241
            .|.|..|| ||.|.                            | ||...|......|.....|..
  Fly   250 EGICYQFNGLRPKDIYRDEKFISYVDPDVVDFNKYFDVDLPPW-NNITGNWSLDTGFVDQGQNAY 313

  Fly   242 AQRAI-GGLRYGLSVVVRYKDDNYD-PLQSYSYGVKLLIQEADAFPSAHSAAKFIAFNSETFAAV 304
            .||.: ..::.|....::....|:| ..:|:..|.|:.:...::.|........:....|...:|
  Fly   314 PQRTVFSSVKNGFFAFLQGLQHNFDYDCRSFKQGYKVFLNSPESVPLTTGNYILVPHGDEVLVSV 378

  Fly   305 RPQETFCSSAVKALIIEERNCVFQNEFPMRYFSDYVYPNCELNCRVTNMVKFCGCHTYFFDFNRT 369
            .|.....:..:..:..|:|.|:|.:|..:|:|..|...||:..|.....|..|||..::.. ...
  Fly   379 LPAYVVSTDNLHEITPEKRQCLFDDERSLRFFRSYSQSNCQTECLANYTVSKCGCAKFWMP-KPL 442

  Fly   370 SDRICTFRDIPCLVDNFGRLLLICSKYSDFNRLLSANIITRKKSTQCYCPLTCEHIDYDVQLTNF 434
            ...:|..:||.|.......|      |:.......|..|.......|.|...|..::|:.:::..
  Fly   443 GTPVCGLKDINCYTSAQDEL------YTLMQNQTMAKSIDESVDITCNCMPACTSLEYNFEISRA 501

  Fly   435 PLELNMPVADKFYSGLAKNDGV---LHVFINSFSYRRLRRDLLSNMVTLVSNLGSAFSLFVGMSM 496
            ..::...:. .|.......|.:   |.|:.....:..::|.:|..:.||:||.|....||:|:|.
  Fly   502 KYDVAKTIR-AFREEYEHTDAIGSRLSVYFKEHQFTAIKRTILFGVSTLISNCGGICGLFMGISC 565

  Fly   497 LSVVEIIYYFSVIL------RKNYKLECETRSQMLHKK 528
            ||.:|:||:|.:.:      |:.:|::.:....:..:|
  Fly   566 LSFLELIYFFCMRICGSCRDRRKHKIQQQNSVDLPEEK 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	None
ppk	NP_477232.1	ASC	69..574	CDD:279230	117/526 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456725
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D112386at6656
OrthoFinder	1	1.000	-	-		FOG0000867
OrthoInspector	1	1.000	-	-		otm24766
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.950