Protein Alignment Nach and Asic2

DIOPT Version :9

• Sequence 1: NP_001334724.1
• Gene: Nach / 36864
• FlyBaseID: FBgn0024319
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_037024.2
• Gene: Asic2 / 25364
• RGDID: 2017
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 103/538 - (19%)
• Similarity: 189/538 - (35%)
• Gaps: 155/538 - (28%)

  Fly    31 CATSSIHGLKYTRDEDTNKIVHLVWLLISVVMFICAVVMARTFYMDYRSSPTRMNVESDNTPVNR 95
            ||..:..|..:.|        ..:|:|.........:..:....:.:.|.|:...|..:.:  .:
  Rat    73 CAGRTAAGGSFQR--------RALWVLAFCTSLGLLLSWSSNRLLYWLSFPSHTRVHREWS--RQ 127

  Fly    96 LYFPPVTICPDVLFNMQKSEAFLNTLRLPKGAELRGILRKLHIFY-----GFML----------- 144
            |.||.||:|.:            |.||.|:       |.|..::|     |.:|
  Rat   128 LPFPAVTVCNN------------NPLRFPR-------LSKGDLYYAGHWLGLLLPNRTARPLVSE 173

  Fly   145 ----DDERYSAEDIEQMEALLFLNNLTIP---------EFVEHLRWNCDEILYRCRFNGEIM--- 193
                |:.|      .|....|....|.:|         .|::.|....:::|..|::.||:.
  Rat   174 LLRGDEPR------RQWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKYRGELCGPH 232

  Fly   194 DCSKIFQLSKTFFGHCCSFNLRQKGWVNNKLNNLESFKVFHLNSLNFTAQRAIGGLRYGLSVVVR 258
            :.|.:|    |.:|.|..||..:.|                 ..|..|.:   ||...||.:::.
  Rat   233 NFSSVF----TKYGKCYMFNSGEDG-----------------KPLLTTVK---GGTGNGLEIMLD 273

  Fly   259 YKDDNYDPL------QSYSYGVKLLIQEADAFPSAHSAAKFIAFNSETFAAVRPQE-TF------ 310
            .:.|.|.|:      .::..|||:.|......|........:|...:||.|.:.|. |:
  Rat   274 IQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWG 338

  Fly   311 -CSSAVKALIIEERNCVFQNEFPMRYFSDYVYPNCELNCRVTNMVKFCGCHTYFFDFNRTSDRIC 374
             |.|               :|..:.:|..|....|.::|....:|:.|.|......
  Rat   339 ECRS---------------SEMGLDFFPVYSITACRIDCETRYIVENCNCRMVHMP--------- 379

  Fly   375 TFRDIP-CLVDNFGRLLLICSKYSDFNRLLSANIITRKKSTQCYCPLTCEHIDYDVQLT--NFP- 435
              .|.| |..:....    |::       .:..::..|.|..|.|...|....|:.:|:  ..|
  Rat   380 --GDAPFCTPEQHKE----CAE-------PALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPS 431

  Fly   436 ------LELNMPVADKFYSGLAKNDGVLHVFINSFSYRRLRRDLLSNMVTLVSNLGSAFSLFVGM 494
                  ||.....::|:   :::|..||.:|..:.:|..:.:.....:..|:.::|....||:|.
  Rat   432 KTSAKYLEKKFNKSEKY---ISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGA 493

  Fly   495 SMLSVVEIIYYFSVILRK 512
            |:|:::|:..|...::::
  Rat   494 SLLTILELFDYIYELIKE 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	None
Asic2	NP_037024.2	ENaC	64..557	CDD:273304	103/538 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345622
Domainoid	1	1.000	111	1.000	Domainoid score	I6095
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8907
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850