DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nach and mec-4

DIOPT Version :9

Sequence 1:	NP_001334724.1	Gene:	Nach / 36864	FlyBaseID:	FBgn0024319	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_510712.2	Gene:	mec-4 / 181728	WormBaseID:	WBGene00003168	Length:	768	Species:	Caenorhabditis elegans

Alignment Length:	382	Identity:	87/382 - (22%)
Similarity:	140/382 - (36%)	Gaps:	86/382 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 EHLRWNCDEILYRCRFNGEIMDCSKIFQLS-KTFFGHCCSFNLRQKGWVNNKLNNLESFKVFHLN 236
            |.|.....|::::|.|||:..|....|... ...||.|.:||                    |..
Worm   437 ERLSTTKRELVHKCSFNGKACDIEADFLTHIDPAFGSCFTFN--------------------HNR 481

  Fly   237 SLNFTAQRAIGGLRYGLSVVVRYKDDNYDPLQSYSYGVKLLIQEADAFPSAHSAAKFIAFNSETF 301
            ::|.|:.||  |..|||.::|.....:|.| .:.:.||:|.|.:.:.||.           .:||
Worm   482 TVNLTSIRA--GPMYGLRMLVYVNASDYMP-TTEATGVRLTIHDKEDFPF-----------PDTF 532

  Fly   302 AAVRPQETFCSSAVKALIIEERNCVFQNEFPMRYFSDYVYPN-------CELNCRVTNMVKFCGC 359
            ....|.....|..::...:......:.:..|....|||:|.|       |..:|....::|.|.|
Worm   533 GYSAPTGYVSSFGLRLRKMSRLPAPYGDCVPDGKTSDYIYSNYEYSVEGCYRSCFQQLVLKECRC 597

  Fly   360 HTYFFDFNRTSDRICTFRDIP----CLVDNFGRLLLICSKYSDFNRLLSANIITRKKSTQCYCPL 420
            ....|.....: |.|...| |    ||          .::.:|...|        ..|.:|.|..
Worm   598 GDPRFPVPENA-RHCDAAD-PIARKCL----------DARMNDLGGL--------HGSFRCRCQQ 642

  Fly   421 TCEHIDYDVQLT--NFP-LELNMPV---------ADKFYSGLAKNDGVLHVFINSFSYRRLRRDL 473
            .|....|.|..:  .:| |.|.:.:         .:|.|.   :|..::.||....::..|....
Worm   643 PCRQSIYSVTYSPAKWPSLSLQIQLGSCNGTAVECNKHYK---ENGAMVEVFYEQLNFEMLTESE 704

  Fly   474 LSNMVTLVSNLGSAFSLFVGMSMLSVVEIIYYFSVILRKNYKLECETRSQMLHKKPK 530
            ....|.|:::.|....|:.|:|.|:..|.::.|   |...| :..| .:..|:||.|
Worm   705 AYGFVNLLADFGGQLGLWCGISFLTCCEFVFLF---LETAY-MSAE-HNYSLYKKKK 756

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	None
mec-4	NP_510712.2	deg-1	86..736	CDD:273309	79/355 (22%)
		ASC	87..>172	CDD:279230
		ASC	<428..739	CDD:295594	80/361 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162289
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750