Protein Alignment Nach and unc-8

DIOPT Version :9

• Sequence 1: NP_001334724.1
• Gene: Nach / 36864
• FlyBaseID: FBgn0024319
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001294293.1
• Gene: unc-8 / 177494
• WormBaseID: WBGene00006748
• Length: 778
• Species: Caenorhabditis elegans
• Alignment Length: 754
• Identity: 132/754 - (17%)
• Similarity: 239/754 - (31%)
• Gaps: 283/754 - (37%)

  Fly     4 QEELKPEQVDLKVTPFVGYLRRTWSDFCATSSIHGLKYTRDEDTNKIVHLVWLLISVVMFICAVV 68
            ::.|:.:::|...|.    ::..|.||||.:|.||:.|.  ..::.....||    ..:|:|.::
 Worm    86 RKSLRSQKIDYHTTT----IKSLWFDFCARTSSHGIPYV--ATSSFFGRYVW----AALFMCMLM 140

  Fly    69 --MARTF-----YMDYRS--------------SPTRMNVE------------------------- 87
              :.:|:     |:.||:              :.|..|:.
 Worm   141 AFLLQTYWTMSEYLQYRTIIEMQLQFEAAAFPAATVCNLNAFKYSELTQYEEIKEGFDYWERVIN 205

  Fly    88 ----SDNTPV------------------NRLYFP------------PV----------------- 101
                ||:...                  ::|.||            ||
 Worm   206 ARMMSDSMKPGGDILEAISVRKKRSKSRDQLLFPIDDEDLEGAVYQPVFVRCTCMNMEQCVPNRN 270

  Fly   102 ------TIC---------------PDVLFNMQKSE--AFLNTLRLPKGAELRGILRKLH------ 137
                  :||               |..::.::|..  :..||...|.|......:.|.:
 Worm   271 PLEVNASICMCFEDVTRGLIWPCYPTSVWTVKKCSGCSISNTCPDPDGPNASKQIAKHNSPLPCL 335

  Fly   138 ---IFYGFML-----------------------------DDERYSAEDI--------EQMEALLF 162
               |.:..|:                             .:|.:...|:        :..|.|:|
 Worm   336 CQSISHHCMVHPKDEIRWWNPNNYTVYSVTEPPTTEITETEEAFGLSDLKDAGAITTQTKENLIF 400

  Fly   163 LNNLTIPEFVEHLRWNCDEILYRCRFNGEIMDCSKIFQLSKTF-------FGHCCSFNLRQKGWV 220
            |......|...:|.:..:|.:.||.||.:  |||    :.:.|       :|:|.:||..
 Worm   401 LVAALPRETRRNLSYTLNEFVLRCSFNSK--DCS----MERDFKLHVDPEYGNCYTFNFN----- 454

  Fly   221 NNKLNNLESFKVFHLNSLNFTAQRAIGGLRYGLSVVVRYKDDNYDPLQSYSYGVKLLIQEAD--A 283
                           :|:.....||  |..|||.:::.....:|.| .:.:.||:|::.|.|  .
 Worm   455 ---------------DSVELKNSRA--GPMYGLRLLLNVHQSDYMP-TTEAAGVRLVVHEQDQEP 501

  Fly   284 FPSAHSAAKFIAFNSETFAAVRPQETFCSSAVKALIIEERNCVFQN------EFPMRYFSDYVYP 342
            ||             :||....|.....|..:|...:...:..:.|      ..|..|...|...
 Worm   502 FP-------------DTFGYSAPTGFISSFGLKTKELHRLSAPWGNCSDTFRPVPYIYNEHYSPE 553

  Fly   343 NCELNCRVTNMVKFCGCHTYFFDFNRTSDRICTFR---DIPCLVDNFGRLLLICSKYSDFNRLLS 404
            .|..||....:::.|||....|.......|.|..:   |..||.:       :.|....::.|
 Worm   554 GCHRNCFQLKVLEICGCGDPRFPLPSEEHRHCNAKSKIDRQCLSN-------LTSDSGGYHHL-- 609

  Fly   405 ANIITRKKSTQCYCPLTCEHIDYDVQLT-------NFPLELNMP-VADKFYSGLA------KNDG 455
                    ..||.|...|....::...:       ||.:..:.| |:|.|....|      :|..
 Worm   610 --------HEQCECRQPCHEKVFETAYSASAWPSQNFKIGTDCPAVSDIFNDTEACTEYYRQNTA 666

  Fly   456 VLHVFINSFSYRRLRRDLLSNMVTLVSNLGSAFSLFVGMSMLSVVEI---------IYYFSVILR 511
            .:.::....::..|:......:|.|.|:.|....|::|.|:::..|.         :.||..|:.
 Worm   667 YIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWIGFSVITFAEFAELFCEICKLMYFKGIVY 731

  Fly   512 KNYKLECE--TRSQMLH-----KKPKFAWPKANDTHSKE 543
            ...|::.:  |.|.::|     :.||.:.|..::..:.|
 Worm   732 VQKKMQGKEYTSSSLMHIDFLQRSPKKSQPGEDEVSTNE 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	None
unc-8	NP_001294293.1	ASC	100..719	CDD:295594	118/687 (17%)
		deg-1	107..716	CDD:273309	117/673 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	95	1.000	Inparanoid score	I3623
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.870