Protein Alignment Nach and acd-2

DIOPT Version :10

• Sequence 1: NP_001334724.1
• Gene: Nach / 36864
• FlyBaseID: FBgn0024319
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001309477.1
• Gene: acd-2 / 171992
• WormBaseID: WBGene00016066
• Length: 693
• Species: Caenorhabditis elegans
• Alignment Length: 578
• Identity: 128/578 - (22%)
• Similarity: 220/578 - (38%)
• Gaps: 140/578 - (24%)

  Fly    20 VGYLRRTWSDFCATSSIHGLK---YTRDEDTNKIVHLVWLLISVVMFICAVVMARTFYM--DYRS 79
            ||...|....|.:|:::||.|   |.:.     :....|:||  |....|::..:.|.:  .|.|
 Worm    73 VGSAFRETKHFSSTTTMHGPKRIFYGKG-----VARAFWMLI--VGLALAMLCFQIFILLQMYFS 130

  Fly    80 SPTRMNVESDNTPVNR--LYFPPVTICPDVLFNMQKSEAFLNTLRLPKGAELRG----ILRKLHI 138
            .||...|   :..||.  :.||.||:|.   ||..| ::::..|.:  ..:|.|    .|.:.::
 Worm   131 KPTLSQV---SFIVNEGGMDFPAVTVCN---FNPIK-KSYVRELNV--SGDLTGETLEYLLQTNM 186

  Fly   139 FYGFMLDD-ERYSAEDIEQMEALLFLNNLTIPEFVEHLR---WNCDEILYRCRFNGEIMDCSKIF 199
            ...|:..: :|::.::... ||..:..|.|..:.::.||   ::|.|:...|.|.|...||.|..
 Worm   187 DAMFLFSNLDRHNLKETHD-EAETYFQNHTDFQIIKFLRTAGYDCGEMFMTCYFGGRRFDCCKYM 250

  Fly   200 QLSKTFFGHCCSFNLRQKG--WVNNKLNNLESFKVFHLNSLNFTAQRAIGGLRYGLSVVV----- 257
            :...|..|.|...:||...  |:..:::                     .|...||.:||
 Worm   251 KQKVTSLGKCWELDLRNLAPEWMRKQIS---------------------PGSEAGLQIVVDAQLE 294

  Fly   258 -RYKDDNYDP----LQSYSYGVKLLIQEADAFPSAHSAAKFIAFNSETFAAVRPQETFCSSAVKA 317
             ..|.:|.|.    ...|..|.:..|         |.........||.. :|.|..| ..||:|.
 Worm   295 EELKGENDDAKAIFSDIYENGFRYFI---------HPPGTNAQLTSEGI-SVSPSRT-VYSAIKT 348

  Fly   318 LI--IEER----NCVFQNEFPMRY--FSDYVYPNCELNCRVTNMVKFCGC--HTYFFDFNRTSDR 372
            :.  :..|    ||  ...:|..|  |..|....|...|........|||  .||..|..:   :
 Worm   349 VTHNLLNRGNWGNC--SENWPEGYNTFLSYSASACRALCIAQFFNDTCGCAPFTYNVDGRK---K 408

  Fly   373 ICT-FRDIPCLVDNFGRLLLICSKYSDFNRLLSANIITRKKSTQCYCPL-TCEHIDYDVQLTNF- 434
            ||. :..|.|: ||.                     :.:|.:...|..| .||....:.|.|::
 Worm   409 ICAPYESITCM-DNH---------------------MLKKVNGTDYLELPDCEECHMECQSTSYT 451

  Fly   435 ------------PLELNMPVADKFYSGLAKNDGVLHVFINSFSYRRLRRDLLSNMVTLVSNLGSA 487
                        .||....:::|..:.:..|..|:::|.....|....:...:::..::|::|..
 Worm   452 SYNSYGDGFNRGSLEWLKKISNKSETHIKNNVAVINIFFLEMFYTSYSQVQATSLTEILSDIGGN 516

  Fly   488 FSLFVGMSMLSVVEIIYYFSVILRKNYKLECETRSQMLHKKPKFAWPKANDTHSKEQK 545
            ..:|:|||::::.|:..:||.|.   :.:..:.|.|.::.|         .||.||::
 Worm   517 MGMFLGMSVITITELSLFFSKIF---WIMVSKRRRQYMYSK---------KTHEKEKE 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nach	NP_001334724.1	ASC	30..505	CDD:459966	115/526 (22%)
acd-2	NP_001309477.1	ASC	83..531	CDD:459966	114/523 (22%)